Document Type

Article

Publication Date

2015

DOI

10.1063/1.49333367

Publication Title

Physics of Plasmas

Volume

22

Issue

122001

Pages

1-6

Abstract

The interaction of low temperature plasma with liquids is a relevant topic of study to the field of plasma medicine. This is because cells and tissues are normally surrounded or covered by biological fluids. Therefore, the chemistry induced by the plasma in the aqueous state becomes crucial and usually dictates the biological outcomes. This process became even more important after the discovery that plasma activated media can be useful in killing various cancer cell lines. Here, we report on the measurements of concentrations of hydrogen peroxide, a species known to have strong biological effects, produced by application of plasma to a minimum essential culture medium. The activated medium is then used to treat SCaBER cancer cells. Results indicate that the plasma activated medium can kill the cancer cells in a dose dependent manner, retain its killing effect for several hours, and is as effective as apoptosis inducing drugs.

Original Publication Citation

Mohades, S., Laroussi, M., Sears, J., Barekzi, N., & Razavi, H. (2015). Evaluation of the effects of a plasma activated medium on cancer cells. Physics of Plasmas, 22(122001), 1-6. doi: 10.1063/1.4933367