A selection of faculty publications from the Department of Medical Diagnostics and Translational Sciences, College of Health Sciences, Old Dominion University.
Submissions from 2024
HSP70 is a Critical Regulator of HSP90 Inhibitor's Effectiveness in Preventing HCL-Induced Chronic Lung Injury and Pulmonary Fibrosis, Ruben M. L. Colunga Biancatelli, Pavel A. Solopov, Tierney Day, Betsy Gregory, Michael Osei-nkansah, Christiana Dimitropoulou, and John D. Catravas
Synergistic Effects of Nanosecond Pulsed Plasma and Electric Field on Inactivation of Pancreatic Cancer Cells In Vitro, Edwin A. Oshin, Zobia Minhas, Ruben M. L. Colunga Biancatelli, John D. Catravas, Richard Heller, Siqi Guo, and Chunqi Jiang
Submissions from 2023
Identification of Proteins Involved in Cell Membrane Permeabilization by Nanosecond Electric Pulses (nsEP), Giedre Silkuniene, Uma Mangalanathan, Alessandra Rossi, Peter A. Mollica, Andrei G. Pakhomov, and Olga N. Pakhomova
Combined 3D Bioprinting and Tissue-Specific ECM System Reveals the Influence of Brain Matrix on Stem Cell Differentiation, Martina Zamponi, Peter A. Mollica, Yara Khodour, Julie S. Bjerring, Robert D. Bruno, and Patrick C. Sachs
Submissions from 2022
NPGREAT: Assembly of the Human Subtelomere Regions with the Use of Ultralong Nanopore Reads and Linked Reads, Eleni Adam, Desh Ranjan, and Harold Riethman
HSP90 Inhibitors Modulate SARS-CoV-2 Spike Protein Subunit 1-Induced Human Pulmonary Microvascular Endothelial Activation and Barrier Dysfunction, Ruben Manuel Luciano Colunga Biancatelli, Pavel Solopov, Betsy W. Gregory, Yara Khodour, and John D. Catravas
Optimizing Antidotal Treatment with the Oral HSP90 Inhibitor TAS-116 Against Hydrochloric Acid-Induced Pulmonary Fibrosis in Mice, Pavel A. Solopov, Ruben Manuel Luciano Colunga Biancatelli, Christiana Dimitropolou, Tierney Day, and John Catravas
Submissions from 2021
Analysis of Subtelomeric REXTAL Assemblies Using QUAST, Tunazzina Islam, Desh Ranjan, Mohammad Zubair, Eleanor Young, Ming Xiao, and Harold Riethman
Dietary Phytoestrogens Ameliorate Hydrochloric Acid-Induced Chronic Lung Injury and Pulmonary Fibrosis in Mice, Pavel Solopov, Ruben Manuel Luciano Colunga Biancatelli, Christiana Dimitropoulou, and John D. Catravas
Picosecond Pulsed Electric Fields and Promise in Neurodegeneration Research, Martina Zamponi, Ross Petrella, and Peter A. Mollica
Submissions from 2020
Single-Molecule Analysis of Subtelomeres and Telomeres in Alternative Lengthening of Telomeres (ALT) Cells, Heba Z. Abid, Jennifer McCaffrey, Kaitlin Raseley, Eleanor Young, Katy Lassahn, Dharma Varapula, Harold Riethman, and Ming Xiao
Quercetin and Vitamin C: An Experimental, Synergistic Therapy for the Prevention and Treatment of SARS-CoV-2 Related Disease (COVID-19), Ruben Manuel Luciano Colunga Biancatelli, Max Berrill, John D. Catravas, and Paul Ellis Marik
Comprehensive Analysis of Human Subtelomeres by Whole Genome Mapping, Eleanor Young, Heba Z. Abid, Pui-Yan Kwok, Harold Riethman, and Ming Xiao
Submissions from 2019
The Revolution Will Be Open-Source: How 3D Bioprinting Can Change 3D Cell Culture, Robert D. Bruno, John Reid, and Patrick C. Sachs
A 3D Bioprinter Platform for Mechanistic Analysis of Tumoroids and Chimeric Mammary Organoids, John A. Reid, Xavier-Lewis Palmer, Peter A. Mollica, Nicole Northam, Patrick C. Sachs, and Robert D. Bruno
Nanosecond Pulsed Electric Fields Induce Endoplasmic Reticulum Stress Accompanied by Immunogenic Cell Death in Murine Models of Lymphoma and Colorectal Cancer, Alessandra Rossi, Olga N. Pakhomova, Peter A. Mollica, Maura Casciola, Uma Mangalanathan, Andrei G. Pakhomov, and Claudia Muratori
Mechanisms and Immunogenicity of nsPEF-Induced Cell Death in B16F10 Melanoma Tumors, Alessandra Rossi, Olga N. Pakhomova, Andrei G. Pakhomov, Samantha Weygandt, Anna A. Bulysheva, Len E. Murray, Peter A. Mollica, and Claudia Muratori
Submissions from 2018
Wild-Type p53 Enhances Endothelial Barrier Function by Mediating RAC1 Signalling and RhoA Inhibition, Nektarios Barabutis, Christiana Dimitropoulou, Betsy Gregory, and John D. Catravas
Electrotransfer of Different Control Plasmids Elicits Different Antitumor Effectiveness in B16.F10 Melanoma, Masa Bosnjak, Tanjo Jesenko, Urska Kamensek, Gregor Sersa, Jaka Lavrencak, Loree Heller, and Maja Cemazar
Direct Crystal Formation from Micronized Bone and Lactic Acid: The Writing on the Wall for Calcium-Containing Crystal Pathogenesis in Osteoarthritis?, Anna A. Bulysheva, Nardos Sori, and Michael P. Francis
Coordination of Different Ligands to Copper(II) and Cobalt(III) Metal Centers Enhances Zika Virus and Dengue Virus Loads in Both Arthropod Cells and Human Keratinocytes, Shovan Dutta, Michael J. Celestine, Supreet Khanal, Alexis Huddleston, Colin Simms, Jessa Faye Arca, Amlam Mitra, Loree Heller, Piotr Kraj, Michael Ledizet, John F. Anderson, Girish Neelakanta, Alvin A. Holder, and Hameeda Sultana
Epigenetic Alterations Mediate iPSC Normalization of DNA-Repair Expression and TNR Stability in Huntington's Disease, Peter A. Mollica, Martina Zamponi, John Reid, Deepak Sharma, Alyson E. White, Roy C. Ogle, Robert D. Bruno, and Patrick C. Sachs
Pneumatospinning of Collagen Microfibers From Benign Solvents, Seth Polk, Nardos Sori, Nick Thayer, Yas Maghdouri-White, Anna A. Bulysheva, and Michael P. Francis
Consistent and Reproducible Cultures of Large-Scale 3D Mammary Epithelial Structures Using an Accessible Bioprinting Platform, John A. Reid, Peter M. Mollica, Robert D. Bruno, and Patrick C. Sachs
IL-12 Gene Electrotransfer Triggers a Change in Immune Response Within Mouse Tumors, Guilan Shi, Chelsea Edelblute, Sezgi Arpag, Cathryn Lundberg, and Richard Heller
Upregulation of DNA Sensors in B16.F10 Melanoma Spheroid Cells After Electrotransfer of pDNA, Katarina Znidar, Masa Bosnjak, Tanja Jesenko, Loree C. Heller, and Maja Cemazar
Tumor Cell Death After Electrotransfer of Plasmid DNA is Associated With Cytosolic DNA Sensor Upregulation, Katarina Znidar, Masa Bosnjak, Nina Semenova, Olga N. Pakhomova, Loree Heller, and Maja Cemazar
Submissions from 2017
Mammary Extracellular Matrix Directs Differentiation of Testicular and Embryonic Stem Cells to Form Functional Mammary Glands In Vivo, Robert D. Bruno, Jodie M. Fleming, Andrea L. George, Corinne A. Boulanger, Pepper Schedin, and Gilbert H. Smith
Electrotransfer of Plasmid DNA Radiosensitizes B16F10 Tumors Through Activation of Immune Response, Richard Heller
Anaplasma Phagocytophilum Infection Modulates Expression of Megakaryocyte Cell Cycle Genes Through Phosphatidylinositol-3-Kinase Signaling, Supreet Khanal, Hameeda Sultana, John D. Catravas, Jason A. Carlyon, and Girish Neelakanta
A Neighborhood-Wide Association Study (NWAS): Example of Prostate Cancer Aggressiveness, Shannon M. Lynch, Nandita Mitra, Michelle Ross, Craig Newcomb, Karl Dailey, Tara Jackson, Charnita M. Zeigler-Johnson, and Harold Riethman
High-Throughput Single-Molecule Telomere Characterization, Jennifer McCaffrey, Eleanor Young, Katy Lassahn, Justin Sibert, Steven Pastor, Harold Riethman, and Ming Xiao
Activation of the Phospholipid Scramblase TMEM16F by Nanosecond Pulsed Electric Field (nsPEF) Facilitates Its Diverse Cytophysiological Effects, Claudia Muratori, Andrei G. Pakhomov, Elena Gianulis, Jade Meads, Maura Casciola, Peter A. Mollica, and Olga N. Pakhomova
Preferential Lineage-Specific Differentiation of Osteoblast-Derived Induced Pluripotent Stem Cells into Osteoprogenitors, Casey L. Roberts, Silvia S. Chen, Angela C. Murchison, Rebecca A. Ogle, Michael P. Francis, Roy C. Ogle, and Patrick C. Sachs
Tissue Specific Microenvironments: A Key Tool for Tissue Engineering and Regenerative Medicine, Patrick C. Sachs, Peter A. Mollica, and Robert D. Bruno
Ebola virus - Epidemiology, Diagnosis, and Control: Threat to Humans, Lessons Learnt, and Preparedness Plans - an Update on Its 40 Year's Journey, Raj Kumar Singh, Kuldeep Dhama, Yashpal Singh Malik, Muthannan Andavar Ramakrishnan, Kumaragurubaran Karthik, Rekha Khandia, Ruchi Tiwari, Ashok Munjal, Mani Saminathan, Perumal Arumugam, and Sunil Kumar Joshi
Neurotrophic Factors NGF, GDNF and NTN Selectively Modulate HSV1 and HSV2 Lytic Infection and Reactivation in Primary Adult Sensory and Autonomic Neurons, Andy Y. Yanez, Telvin Harrell, Heather J. Sriranganathan, Angela M. Ives, and Andrea S. Bertke
High-Throughput Single-Molecule Mapping Links Subtelomeric Variants and Long-Range Haplotypes with Specific Telomeres, Eleanor Young, Steven Pastor, Ramakrishnan Rajagopalan, Jennifer McCaffrey, Justin Sibert, Angel C. Y. Mak, Pui-Yan Kwok, Harold Riethman, and Ming Xiao
Submissions from 2016
Vascular Endothelial Growth Factor-A Gene Electrotransfer Promotes Angiogenesis in a Porcine Model of Cardiac Ischemia, Anna A. Bulysheva, Barbara Hargrave, Nina Burcus, Cathryn G. Lundberg, Len Murray, and Richard Heller
Modeling Early Stage Bone Regeneration With Biomimetic Electrospun Fibrinogen Nanofibers and Adipose-Derived Mesenchymal Stem Cells, Michael P. Francis, Yas M. Moghaddam-White, Patrick C. Sachs, Matthew J. Beckman, Stephen M. Chen, Gary L. Bowlin, Lynne W. Elmore, and Shawn E. Holt
Nanosecond Pulsed Platelet-Rich Plasma (nsPRP) Improves Mechanical and Electrial Cardiac Function Following Myocardial Reperfusion Injury, Barbara Y. Hargrave, Frency Varghese, Nektarios Barabutis, John Catravas, and Christian Zemlin
Race, Ethnicity, Psychosocial Factors, and Telomere Length in a Multicenter Setting, Shannon M. Lynch, M. K. Peek, Nandita Mitra, Krithika Ravichandran, Charles Branas, Elaine Spangler, Wenting Zhou, Electra D. Paskett, Sarah Gehlert, Cecilia DeGraffinreid, Timothy R. Rebbeck, and Harold Riethman
Accessible Bioprinting: Adaptation of a Low-Cost 3D-Printer for Precise Cell Placement and Stem Cell Differentiation, John A. Reid, Peter A. Mollica, Garett D. Johnson, Roy C. Ogle, Robert D. Bruno, and Patrick C. Sachs
Enhanced Osseous Integration of Human Trabecular Allografts Following Surface Modification With Bioactive Lipids, Tiffany Wang, Jack Krieger, Cynthia Huang, Anusuya Das, Michael P. Francis, Roy Ogle, and Edward Botchwey
Submissions from 2015
Designing a Broad-Spectrum Integrative Approach for Cancer Prevention and Treatment, Keith I. Block, Charlotte Gyllenhaal, Leroy Lowe, Amedeo Amedei, A.R.M. Ruhul Amin, Amr Amin, Katia Aquilano, Jack Arbiser, Alexandra Arreola, Alla Arzumanyan, and Patricia Hentosh
Bioactive Lipid Coating of Bone Allografts Direct Engraftment and Fate Determination of Bone Marrow-Derived Cells in Rat GFP Chimeras, Anusuya Das, Claire E. Segar, Yihsuan Chu, Tiffany W. Wang, Yon Lin, Chunxi Yang, and Roy C. Ogle
Donor Platelet Plasma Components Inactivate Sensitive and Multidrug Resistant Acinetobacter Baumannii Isolates, Chelsea M. Edelblute, Olga N. Pakhomova, Fanying Li, Barbara Y. Hargrave, and Loree C. Heller
A Novel Cardiac Muscle-Derived Biomaterial Reduces Dyskinesia and Postinfarct Left Ventricular Remodeling in a Mouse Model of Myocardial Infarction, Daniel M. O'Connor, Nivedita K. Naresh, Bryan A. Piras, Yaqin Xu, Robert S. Smith, and Roy C. Ogle
Therapeutic Targeting of Replicative Immortality, Paul Yaswen, Karen L. MacKenzie, W. Nicol Keith, Patricia Hentosh, Francis Rodier, Jiyue Zhu, Gary L. Firestone, Ander Matheu, Amancio Carnero, and Alan Bilsland
Submissions from 2014
Paracrine-Rescued Lobulogenesis in Chimeric Outgrowths Comprising Progesterone-Receptor-Null Mammary Epithelium and Redirected Wild-Type Testicular Cells, Robert D. Bruno, Corinne A. Boulanger, Sonia M. Rosenfield, Lisa H. Anderson, John P. Lydon, and Gilbert H. Smith
A Potential Mechanism for Extracellular Matrix Induction of Breast Cancer Cell Normality, Robert D. Bruno and Gilbert H. Smith
A Potential Mechanism For Extracellular Matrix Induction of Breast Cancer Cell Normality, Robert D. Bruno and Gilbert H. Smith
Leptin Regulates CD16 Expression on Human Monocytes in a Sex-Specific Manner, Joseph G. Cannon, Gyanendra Sharma, Gloria Sloan, Christiana Dimitropoulou, R. Randall Baker, Andrew Mazzoli, Barbara Kraj, Anthony Mulloy, and Miriam Cortez-Cooper
Submissions from 2013
Embryonic Stem Cells Are Redirected to Non-Tumorigenic Epithelial Cell Fate by Interaction with the Mammary Microenvironment, Corinne A. Boulanger, Robert D. Bruno, David L. Mack, Monica Gonzales, Nadia P. Castro, David S. Salomon, and Gilbert H. Smith
Submissions from 2012
Alignment and Composition of Laminin-Polycaprolactone Nanofiber Blends Enhance Peripheral Nerve Regeneration, Rebekah A. Neal, Sunil S. Tholpady, Patricia L. Foley, Nathan Swami, Roy C. Ogle, and Edward A. Botchwey
Submissions from 2011
Follicle-Stimulating Hormone Promotes RANK Expression on Human Monocytes, Joseph G. Cannon, Barbara Kraj, and Gloria Sloan
Submissions from 2005
Improving Clinical Practice Using Clinical Decision Support Systems: A Systematic Review of Trials to Identify Features Critical to Success, Kensaku Kawamoto, Caitlin A. Houlihan, E. Andrew Balas, and David F. Lobach
Submissions from 2004
How Many Slides? Documented Cytotechnologist Workload, Sophie K, Thompson and Eileen Mason
Submissions from 2000
Applications of Wavelet Transforms in Biomedical Optoacoustics, Zibiao Wei, Shujun Yang, Amin N. Dharamsi, and Barbara Hargrave
Submissions from 1999
Insulinlike Growth Factor 1- and 2-Augmented Collagen Gel Repair of Facial Osseous Defects, James S. Toung, Roy C. Ogle, Raymond F. Morgan, and William H. Lindsey
Submissions from 1995
Molecular Cloning and Rare Cleavage Mapping of Human 2P, 6Q, 8Q, 12Q, and 18Q Telomeres, Roberto A. Macina, Ken Morii, Xue-Lan Hu, Dimitri G. Negorev, Chrysanthe Spais, Lisa A. Ruthig, and Harold C. Riethman
Submissions from 1990
Laminin Potentiates Differentiation of PCC4uva Embryonal Carcinoma into Neurons, T. M. Sweeney, Roy C. Ogle, and C. D. Little
Submissions from 1989
Collagen Binding Proteins Derived from the Embryonic Fibroblast Cell Surface Recognize Arginine-Glycine-Aspartic Acid, Roy C. Ogle and Charles D. Little
Embryonic Chicken Fibroblast Collagen Binding Proteins: Distribution, Role in Substratum Adhesion, and Relationship to Integrins, Roy C. Ogle, A. Jeannette Potts, Marchall Yacoe, and Charles D. Little
Submissions from 1988
The Characterization of Ribosomal RNA Gene Chromatin from Physarum Polycephalum, Sally A. Amero, Vicky L. Montoya, Wendy L. Murdoch, Roy C. Ogle, John L. Keating, and Robert M. Grainger
The Purification of Ribosomal RNA Gene Chromatin from Physarum Polycephalum, Sally A. Amero, Roy C. Ogle, John L. Keating, Vicky L. Montoya, Wendy L. Murdoch, and Robert M. Grainger
Laminin Receptors for Neurite Formation, H. K. Kleinman, Roy C. Ogle, F. B. Cannon, C. D. Little, T. M. Sweeney, and L. Luckenbill-Edds