T-Cells May Represent a Novel Biomarker for Female Pattern Hair Loss

Authors

• Juan Marrero Berrios, Pennsylvania Hospital
• Iain Noel Encarnacion, Macon & Joan Brock Virginia Health Sciences at Old Dominion UniversityFollow
• Noelle Desir, Weill Cornell Medical College
• Aman Prasad, Perelman School of Medicine at the University of Pennsylvania
• Matthew Hedberg, Perelman School of Medicine at the University of Pennsylvania
• Susan Taylor, Perelman School of Medicine at the University of Pennsylvania
• John T. Seykora, Perelman School of Medicine at the University of Pennsylvania

ORCID

0009-0006-4972-7093 (Encarnacion)

Document Type

Article

Publication Date

2026

DOI

10.1016/j.jaad.2026.09.006

Publication Title

Journal of the American Academy of Dermatology

Volume

Advance online publication

Pages

9 pp.

Abstract

[Introduction] Androgenetic alopecia (AGA) is a common non-scarring alopecia classically attributed to androgen sensitivity and genetics. Histopathologic studies have identified perifollicular and perivascular lymphocytic and histiocytic infiltrates, through the composition and clinical relevance of this infiltrate have not been fully characterized.¹ Our study aims to address this gap through detailed quantitative immunohistochemical characterization (IHC) of the inflammatory infiltrate in female patients with AGA compared to telogen effluvium (TE), a non-inflammatory control.

Rights

© 2026 The Authors.

Published under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) License.

Original Publication Citation

Berrios, J. M., Encarnacion, I. N., Desir, N., Prasad, A., Hedberg, M., Taylor, S., & Seykora, J. T. (2026). T-cells may represent a novel biomarker for female pattern hair loss. Journal of the American Academy of Dermatology. Advance online publication. https://doi.org/10.1016/j.jaad.2026.09.006

Repository Citation

Berrios, J. M., Encarnacion, I. N., Desir, N., Prasad, A., Hedberg, M., Taylor, S., & Seykora, J. T. (2026). T-cells may represent a novel biomarker for female pattern hair loss. Journal of the American Academy of Dermatology. Advance online publication. https://doi.org/10.1016/j.jaad.2026.09.006