Location

Old Dominion University, Learning Commons at Perry Library, West Foyer

Start Date

8-4-2017 8:30 AM

End Date

8-4-2017 10:00 AM

Description

Glaucoma patients only can instill glaucoma eye drops. This results in 1-7% absorption of the medication. Surveys show that patients forget to take their medication and have difficulty inserting their eye drops. Researchers at the Massachusetts Eye and Ear Infirmary have developed latanoprost drug-dispensing hydrogel soft contact lenses that dispense the drug to help facilitate the process. However, some glaucoma patients do not respond to latanoprost because they have uveitic glaucoma or do not want to experience latanoprost’s ocular side effects. Patients need an alternative which can be inserted into these contact lenses. Another commonly used glaucoma drug is timolol which can be an option. Timolol has fewer ocular side effects, is less expensive to buy, and has extended drug release rates like latanoprost. This alternative would let patients who do not respond well to latanoprost a choice to try timolol-dispensing contact lenses once they become available to consumers.

Comments

Research Mentor: Professor Boyes

Keywords: soft drug-dispensing contact lenses, latanoprost, timolol, polymer film, drug delivery

Presentation Type

Poster

Potdar-FinalPaper.pdf (121 kB)
Final Paper of Neha Potdar

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Apr 8th, 8:30 AM Apr 8th, 10:00 AM

Latanoprost and Timolol in Hydrogel Soft Drug-Dispensing Contact Lenses: A Comparative Analysis

Old Dominion University, Learning Commons at Perry Library, West Foyer

Glaucoma patients only can instill glaucoma eye drops. This results in 1-7% absorption of the medication. Surveys show that patients forget to take their medication and have difficulty inserting their eye drops. Researchers at the Massachusetts Eye and Ear Infirmary have developed latanoprost drug-dispensing hydrogel soft contact lenses that dispense the drug to help facilitate the process. However, some glaucoma patients do not respond to latanoprost because they have uveitic glaucoma or do not want to experience latanoprost’s ocular side effects. Patients need an alternative which can be inserted into these contact lenses. Another commonly used glaucoma drug is timolol which can be an option. Timolol has fewer ocular side effects, is less expensive to buy, and has extended drug release rates like latanoprost. This alternative would let patients who do not respond well to latanoprost a choice to try timolol-dispensing contact lenses once they become available to consumers.