Date of Award

Spring 1976

Document Type


Degree Name

Master of Science (MS)


Biological Sciences



Committee Director

Beverly Anne Weeks

Committee Member

J. H. Richardson

Committee Member

H. D. Whitten

Call Number for Print

Special Collections LD4331.B46 B87


Blastospore and mycelial cytoplasmic extracts from four strains of Candida albicans, varying in virulence, were compared by sodium dodecyl sulfate (SDS) polyacrylamide disc gel electrophoresis Cytoplasmic extracts were made by disrupting the cultures in a Braun homogenizer followed by ultracentrifugation. The supernatant fractions were then resolved on polyacrylamide gels containing SDS. Each of the preparations yielded a distinct pattern. There were mycelial specific and blastospore specific protein bands. There were more components resolved from the blastospore phase cytoplasmic extracts than from the mycelial phase cytoplasmic extracts. There were bands common to both phases. These results demonstrate protein components unique to the mycelial phase and unique to the blastospore phase of Candida albicans.


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