Document Type


Publication Date




Publication Title

Mathematical Problems in Engineering




5557320 (1-11)


Inherent safety (IS) refers to a set of measures that enhance the safety level of processes and equipment, rendering additional equipment and/or add-ons. The early design phase of processes is suited best for implementation of IS strategies as some of such strategies either are impossible to be implemented at the operation phase or substantially increase costs. The purpose of this study is to present a new approach called genetic algorithm process optimization (GAPO), by which processes can be made inherently safer even at the operation phase. This study simulates the IS principle, assessing its impact on quantitative risk and the possible consequences of process incidents identified by Hazard and Operation Study (HAZOP). The principle of intensification was simulated through GAPO, and feasibility of implementation was approved by HYSYS. Moreover, the integrated inherent safety index (I2SI) was used to evaluate and quantify the level of IS following implementation of GAPO compared to the initial design. Our result shows that GAPO substantially reduced the risk of consequences and quantitative risks and concomitantly improved the I2SI. The proposed GAPO can be applied to process operation as an approach to enhance IS at no cost and without decrease in production.


Copyright © 2021 Mehdi Jahangiri et al.

This is an open access article distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Data Availability

The data used to support the findings of this study are included within the article.

Original Publication Citation

Jahangiri, M., Moghadasi, A., Kamalinia, M., Sadeghianjahromi, F., & Banaee, S. (2021). Influence of the inherent safety principles on quantitative risk in process industry: Application of genetic algorithm process optimization (GAPO). Mathematical Problems in Engineering, 2021, 1-11, Article 5557320.