Part of the Biotechnology Commons

Works in Biotechnology

2022

3D Bioprinted Structures from Cells of Non-Epithelial Mesodermal and Endodermal Lineage Using a Custom Accessible 3D Bioprinting Platform, Xavier-Lewis Palmer, Annette Berkin, Patrick C. Sachs, Robert D. Bruno
College of Engineering & Technology (Batten) Posters

2021

COVID-19 and Biocybersecurity's Increasing Role on Defending Forward, Xavier Palmer, Lucas N. Potter, Saltuk Karahan
Electrical & Computer Engineering Faculty Publications

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2020

Numerical Modeling of Submicron Particles for Acoustic Concentration in Gaseous Flow, Jizhou Liu, Xiaodong Li, Fang Q. Hu
Mathematics & Statistics Faculty Publications

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2019

DeepEP: A Deep Learning Framework for Identifying Essential Proteins, Min Zeng, Min Li, Fang-Xiang Wu, Yaohang Li, Yi Pan
Computer Science Faculty Publications

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Label-Free MicroRNA Optical Biosensors, Meimei Lai, Gymama Slaughter
Bioelectrics Publications

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Acute Systemic Inflammatory Response to Lipopolysaccharide Stimulation in Pigs Divergently Selected for Residual Feed Intake, Haibo Liu, Kristina M. Feye, Yet T. Nguyen, Anoosh Rakhshandeh, Crystal L. Loving, Jack C. M. Sekkers, Nicholas K. Gabler, Christopher K. Tuggle
Mathematics & Statistics Faculty Publications

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Computational Models for Biomedical Reasoning and Problem Solving, Chung-Hao Chen (Editor), Sen-Ching Samson Cheung (Editor)
Electrical & Computer Engineering Faculty Books

Mechanisms and Immunogenicity of nsPEF-Induced Cell Death in B16F10 Melanoma Tumors, Alessandra Rossi, Olga N. Pakhomova, Andrei G. Pakhomov, Samantha Weygandt, Anna A. Bulysheva, Len E. Murray, Peter A. Mollica, Claudia Muratori
Bioelectrics Publications

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A 3D Bioprinter Platform for Mechanistic Analysis of Tumoroids and Chimeric Mammary Organoids, John A. Reid, Xavier-Lewis Palmer, Peter A. Mollica, Nicole Northam, Patrick C. Sachs, Robert D. Bruno
Medical Diagnostics & Translational Sciences Faculty Publications

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2018

Consistent and Reproducible Cultures of Large-Scale 3D Mammary Epithelial Structures Using an Accessible Bioprinting Platform, John A. Reid, Peter M. Mollica, Robert D. Bruno, Patrick C. Sachs
Medical Diagnostics & Translational Sciences Faculty Publications

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Moderate Heat Application Enhances the Efficacy of Nanosecond Pulse Stimulation for the Treatment of Squamous Cell Carcinoma, Chelsea M. Edelblute, Sigi Guo, Embo Yang, Chunqi Jiang, Karl Schoenbach, Richard Heller
Bioelectrics Publications

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Mechanism of Virus Inactivation by Cold Atmospheric-Pressure Plasma and Plasma-Activated Water, Li Guo, Ruobing Xu, Lu Gou, Zhichao Liu, Yiming Zhao, Dingxin Liu, Lei Zhang, Hailan Chen, Michael G. Kong
Bioelectrics Publications

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Prediction of lncRNA-Disease Associations Based on Inductive Matrix Completion, Chengqian Lu, Mengyun Yang, Feng Luo, Fang-Xiang Wu, Min Li, Yi Pan, Yaohang Li, Jianxin Wang
Computer Science Faculty Publications

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Differential Gene Expression of Chondrocytes in PLGA Scaffolds, Martina Zamponi
Undergraduate Research Symposium

Cell Fragmentation and Permeabilization by a 1 ns Pulse Driven Triple-Point Electrode, Enbo Yang, Joy Li, Michael Cho, Shu Xiao
Bioelectrics Publications

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Upregulation of DNA Sensors in B16.F10 Melanoma Spheroid Cells After Electrotransfer of pDNA, Katarina Znidar, Masa Bosnjak, Tanja Jesenko, Loree C. Heller, Maja Cemazar
Bioelectrics Publications

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Excitation and Injury of Adult Ventricular Cardiomyocytes by Nano- to Millisecond Electric Shocks, Iurii Semenov, Sergey Grigoryev, Johanna U. Neuber, Christian W. Zemlin, Olga N. Pakhomova, Maura Casciola, Andrei G. Pakhomov
Bioelectrics Publications

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Electrotransfer of Different Control Plasmids Elicits Different Antitumor Effectiveness in B16.F10 Melanoma, Masa Bosnjak, Tanjo Jesenko, Urska Kamensek, Gregor Sersa, Jaka Lavrencak, Loree Heller, Maja Cemazar
Bioelectrics Publications

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Dielectric Properties of Isolated Adrenal Chromaffin Cells Determined by Microfluidic Impedance Spectroscopy, A. C. Sabuncu, M. Stacey, G. L. Graviso, N. Semenova, P. T. Vernier, N. Leblanc, I. Chatterjee, J. Zaklit
Bioelectrics Publications

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Nano-Pulse Stimulation for the Treatment of Pancreatic Cancer and the Changes in Immune Profile, Sigi Guo, Niculina I. Burcus, James Hornef, Yu Jing, Chunqi Jiang, Richard Heller, Stephen J. Beebe
Bioelectrics Publications

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2017

High-Throughput Single-Molecule Telomere Characterization, Jennifer McCaffrey, Eleanor Young, Katy Lassahn, Justin Sibert, Steven Pastor, Harold Riethman, Ming Xiao
Medical Diagnostics & Translational Sciences Faculty Publications

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Controllable Moderate Heating Enhances the Therapeutic Efficacy of Irreversible Electroporation for Pancreatic Cancer, Chelsea M. Edelblute, James Hornef, Niculina I. Burcus, Thomas Norman, Stephen J. Beebe, Karl Schoenbach, Richard Heller, Chunqi Jiang, Sigi Guo
Bioelectrics Publications

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Damage-Free Peripheral Nerve Stimulation by 12-ns Pulsed Electric Field, Maura Casciola, Shu Xiao, Andrei G. Pakhomov
Bioelectrics Publications

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Delayed Hypersensitivity to Nanosecond Pulsed Electric Field in Electroporated Cells, Sarah D. Jensen, Vera A. Khorokhorina, Claudia Muratori, Andrei G. Pakhomov, Olga N. Pakhomova
Bioelectrics Publications

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Multi-Material Mesh Representation of Anatomical Structures for Deep Brain Stimulation Planning, Tanweer Rashid
Computational Modeling & Simulation Engineering Theses & Dissertations

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Computational Detection of Protein Structure Components from 3-Dimensional Images Obtained from Cryo-Electron Microscopy, Devin Haslam
Virginias Collegiate Honors Council Conference

Brave New Further-Divided World? Ectogenesis in Context, Nykema Mpama
Virginias Collegiate Honors Council Conference

Modeling Beta-Traces for Beta-Barrels from Cryo-EM Density Maps, Dong Si, Jing He
Computer Science Faculty Publications

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Comparing an Atomic Model or Structure to a Corresponding Cryo-Electron Microscopy Image at the Central Axis of a Helix, Stephanie Zeil, Julio Kovacs, Willy Wriggers, Jing He
Computer Science Faculty Publications

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Electrotransfer of Plasmid DNA Radiosensitizes B16F10 Tumors Through Activation of Immune Response, Monika Savarin, Urska Kamensek, Maja Cemazar, Richard Heller, Gregor Sersa
Bioelectrics Publications

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Hyper-Activation of pp60(Src) Limits Nitric Oxide Signaling by Increasing Asymmetric Dimethylarginine Levels During Acute Lung Injury, Sanjiv Kumar, Xutong Sun, Satish Kumar Noonepalle, Qing Lu, Evgeny Zemskov, Ting Wang, Saurabh Aggarwal, Christine Gross, Shruti Sharma, Ankit A. Sesai, John D. Catravas
Bioelectrics Publications

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Nanosecond Pulsed Electric Field Induced Changes in Cell Surface Charge Density, Diganta Dutta, Xavier-Lewis Palmer, Anthony Asmar, Michael Stacey, Shizhi Qian
Bioelectrics Publications

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Tissue Specific Microenvironments: A Key Tool for Tissue Engineering and Regenerative Medicine, Patrick C. Sachs, Peter A. Mollica, Robert D. Bruno
Medical Diagnostics & Translational Sciences Faculty Publications

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2016

Vascular Endothelial Growth Factor-A Gene Electrotransfer Promotes Angiogenesis in a Porcine Model of Cardiac Ischemia, Anna A. Bulysheva, Barbara Hargrave, Nina Burcus, Cathryn G. Lundberg, Len Murray, Richard Heller
Bioelectrics Publications

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Microbubble Generation By Piezoelectric Transducers For Biomedical Studies, Mohammed Alkhazal
Electrical & Computer Engineering Theses & Dissertations

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Experimental Assessment of Mouse Sociability Using an Automated Image Processing Approach, Frency Varghese, Jessica A. Burket, Andrew D. Benson, Stephen I. Deutsch, Christian W. Zemlin
Electrical & Computer Engineering Faculty Publications

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Inactivation of Acanthamoeba spp. and Other Ocular Pathogens By Application of Cold Atmospheric Gas Plasma, Wayne Heaselgrave, Gilbert Shama, Peter W. Andrew, Michael G. Kong
Bioelectrics Publications

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The Cytotoxic Synergy of Nanosecond Electric Pulses and Low Temperature Leads to Apoptosis, Claudia Muratori, Andrei G. Pakhomov, Elena C. Gianulis, Sarah D. Jensen, Olga N. Pakhomova
Bioelectrics Publications

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2015

ISQuest: Finding Insertion Sequences in Prokaryotic Sequence Fragment Data, Abhishek Biswas, David T. Gauthier, Desh Ranjan, Mohammad Zubair
Computer Science Faculty Publications

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Increased Tissue Temperature Improves Electro-Transfer Mediated Gene Delivery to Skin, Anna Bulysheva, Amy Donate, Chelsea Edelblute, Derrick Jung, Karl Schoenbach, Richard Heller
Bioelectrics Publications

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Sperm DNA Oxidative Damage and DNA Adducts, Hueiwang Anna Jeng, Chih-Hong Pan, Mu-Rong Chao, Wen-Yi Lin
Community & Environmental Health Faculty Publications

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Introduction to Fifth Special Issue on Electroporation-Based Technologies and Treatments, Damijan Miklavčič, Lluis M. Mir, P. Thomas Vernier
Bioelectrics Publications

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Differential Dielectric Responses of Chondrocyte and Jurkat Cells in Electromanipulation Buffers, Ahmet C. Sabuncu, Anthony J. Asmar, Michael W. Stacey, Ali Beskok
Bioelectrics Publications

2014

Concepts of Cancer and a Novel Cancer Therapy: Treating Tumors as an Aggressive Organ, Stephen J. Beebe
Bioelectrics Publications

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Evaluations of a Mechanistic Hypothesis for the Influence of Extracellular Ions on Electroporation Due to High-Intensity, Nanosecond Pulsing, V. Sridhara, R. P. Joshi
Electrical & Computer Engineering Faculty Publications

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2013

Electrotransfer of Single-Stranded or Double-Stranded DNA Induces Complete Regression of Palpable B16.F10 Mouse Melanomas, Loree Heller, Vesba Todorovic, Maja Cemazar
Bioelectrics Publications

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NEXT-Peak: A Normal-Exponential Two-Peak Model for Peak-Calling in ChIP-seq Data, Nak-Kyeong Kim, Rasika V. Jayatillake, John L. Spouge
Mathematics & Statistics Faculty Publications

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Real-Time in vivo Imaging of Size-Dependent Transport and Toxicity of Gold Nanoparticles in Zebrafish Embryos Using Single Nanoparticle Plasmonic Spectroscopy, Lauren M. Browning, Tao Huang, Xiao-Hong Nancy Xu
Chemistry & Biochemistry Faculty Publications

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Response to "Sodium Current Inhibition by Nanosecond Pulsed Electric Field (nsPEF) - Fact or Artifact?" by Verkerk et al, Andrei G. Pakhomov
Bioelectrics Publications

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2012

Inactivation of Bacterial Opportunistic Skin Pathogens by Nonthermal DC-Operated Afterglow Atmospheric Plasma, L. C. Heller, C. M. Edelblute, A. M. Mattson, X. Hao, J. F. Kolb
Bioelectrics Publications

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Microfluidic Impedance Spectroscopy as a Tool for Quantitative Biology and Biotechnology, Ahmet C. Sabuncu, Jie Zhuang, Juergen F. Kolb, Ali Beskok
Mechanical & Aerospace Engineering Faculty Publications

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Long Term Survival of Mice With Hepatocellular Carcinoma after Pulse Power Ablation with Nanosecond Pulsed Electric Fields, X. Chen, J. Zhuang, J. F. Kolb, Karl H. Schoenbach, Stephen J. Beebe
Bioelectrics Publications

2011

Evaluation of Delivery Conditions for Cutaneous Plasmid Electrotransfer Using a Multielectrode Array, Bernadette Ferraro, Loree C. Heller, Yolmari L. Cruz, Siqi Guo, Amy Donate, Richard Heller
Bioelectrics Publications

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Human Endogenous Retrovirus Transcription Profiles of the Kidney and Kidney-Derived Cell Lines, Sonja Haupt, Michele Tisdale, Michelle Vincendeau, Mary Anne Clements, David T. Gauthier, Raymond Lance, O. John Demmes, Adriana Tuqueti-Neves, Elfriede Noessner, Christine Leib-Mösch, Alex D. Greenwood
Biological Sciences Faculty Publications

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Electro-Gene Transfer to Skin Using a Noninvasive Multielectrode Array, Siqi Guo, Amy Donate, Gaurav Basu, Cathryn Lundberg, Loree Heller, Richard Heller
Bioelectrics Publications

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Efficacy of the Pentavalent Rotavirus Vaccine, RotaTeq (RV5), Between Doses of a 3-Dose Series and With Less Than 3 Doses (Incomplete Regimen), Penelope D. Dennehy, Timo Vesikari, David O. Matson, Robbin F. Itzler, Michael J. Dallas, Michelle G. Goveia, Mark J. DiNubile, Penny M. Heaton, Max Ciarlet
Community & Environmental Health Faculty Publications

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2010

Advanced Electroporation Techniques in Biology and Medicine, Andrei G. Pakhomov (Editor), Damijan Miklavcic (Editor), Marko S. Markov (Editor)
Bioelectrics Books

Electrically Mediated Delivery of Plasmid DNA to the Skin, Using a Multielectrode Array, Richard Heller, Yolmari Criz, Loree C. Heller, Richard A. Gilbert, Mark J. Jaroszeski
Bioelectrics Publications

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Apoptosis Initiation and Angiogenesis Inhibition: Melanoma Targets for Nanosecond Pulsed Electric Fields, Xinhua Chen, Juergen F. Kolb, R. James Swanson, Karl H. Schoenbach, Stephen J. Beebe
Bioelectrics Publications

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Quantitative PCR Assay for Mycobacterium Pseudoshottsii and Mycobacterium Shottsii and Application to Environmental Samples and Fishes from the Chesapeake Bay, D. T. Gauthier, K. S. Reece, J. Xiao, M. W. Rhodes, H. I. Kator, R. J. Latour, C. F. Bonzek, J. M. Hoenig, W. K. Vogelbein
Biological Sciences Faculty Publications

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Increased Perfusion and Angiogenesis in a Hindlimb Ischemia Model with Plasmid FGF-2 Delivered by Noninvasive Electroporation, B. Ferraro, Y. L. Cruz, M. Baldwin, D. Coppola, R. Heller
Bioelectrics Publications

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Electroporation-Mediated Delivery of a Naked DNA Plasmid Expressing VEGF to the Porcine Heart Enhances Protein Expression, W. G. Marshall Jr., B. A. Boone, J. D. Burgos, S. I. Gografe, M. K. Baldwin, M. L. Danielson, M. J. Larson, D. R. Caretto, Y. Cruz, B. Ferraro, L. C. Heller, K. E. Ugen, M. J. Jaroszeski, R. Heller
Bioelectrics Publications

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Plasmid Injection and Application of Electric Pulses Alter Endogenous mRNA and Protein Expression in B16.F10 Mouse Melanomas, L. C. Heller, Y. L. Cruz, B. Ferraro, H. Yang, R. Heller
Bioelectrics Publications

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Electric Pulses to Prepare Feeder Cells for Sustaining and Culturing of Undifferentiated Embryonic Stem Cells, Lauren M. Browning, Tao Huang, Xiao-Hong Nancy Xu
Chemistry & Biochemistry Faculty Publications

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2009

A New Pulsed Electric Field Therapy for Melanoma Disrupts the Tumor's Blood Supply and Causes Complete Remission Without Recurrence, Richard Nuccitelli, Xinhua Chen, Andrei G. Pakhomov, Wallace H. Baldwin, Saleh Sheikh, Jennifer L. Pomicter, Wei Ren, Chris Osgood, R. James Swanson, Juergen F. Kolb, Stephen J. Beebe, Karl H. Schoenbach
Bioelectrics Publications

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Intradermal Delivery of Plasmid VEGF(165) by Electroporation Promotes Wound Healing, Bernadette Ferraro, Yolmari Cruz, Domenico Coppola, Richard Heller
Bioelectrics Publications

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Electroporation for the Delivery of DNA-Based Vaccines and Immunotherapeutics: Current Clinical Developments, Angela M. Bodles-Brakhop, Richard Heller, Ruxandra Draghia-Akli
Bioelectrics Publications

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2008

Comparison of Electrically Mediated and Liposome-Complexed Plasmid DNA Delivery to the Skin, Loree C. Heller, Mark J. Jaroszeski, Domenico Coppola, Richard Heller
Bioelectrics Publications

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2007

Optimization of Cutaneous Electrically Mediated Plasmid DNA Delivery Using Novel Electrode, L. C. Heller, M. J. Jaroszeski, D. Coppola, A. N. McCray, J. Hickey, R. Heller
Bioelectrics Publications

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Sensory Genes and Mate Choice: Evidence That Duplications, Mutations, and Adaptive Evolution Alter Variation in Mating Cue Genes and Their Receptors, Lisa Horth
Biological Sciences Faculty Publications

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Potential for Stimulating Host Anti-Tumor Immune Response via RNAi-Mediated Local FOXP3 Knockdown, N. Klaiber
Chemistry & Biochemistry Faculty Publications

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New Frontiers in Ultrasensitive Bioanalysis: Advanced Analytical Chemistry Applications in Nanobiotechnology, Single Molecule Detection, and Single Cell Analysis, Xiao-Hong Nancy Xu
Chemistry & Biochemistry Faculty Books

2006

Evaluation of Toxicity Following Electrically Mediated Interleukin-12 Gene Delivery in a B16 Mouse Melanoma Model, Loree Heller, Kathleen Merkler, Jeffrey Westover, Yolmari Cruz, Domenico Coppola, Kaaron Benson, Adil Daud, Richard Heller
Bioelectrics Publications

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Plasma Membrane Voltage Changes During Nanosecond Pulsed Electric Field Exposure, W. Frey, R. O. Price, P. F. Blackmore, R. P. Joshi, R. Nuccitelli, S. J. Beebe, K. H. Schoenbach, J. F. Kolb
Bioelectrics Publications

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2005

Selective Field Effects on Intracellular Vacuoles and Vesicle Membranes with Nanosecond Electric Pulses, Ephrem Tekle, Hammou Oubrahim, Sergey M. Dzekunov, Juergen F. Kolb, Karl H. Schoenbach
Bioelectrics Publications

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High-Temperature Fluorescent In Situ Hybridization for Detecting Escherichia coli in Seawater Samples, Using rRNA-Targeted Oligonucleotide Probes and Flow Cytometry, Ying Zhong Tang, Karina Yew Hoong Gin, Tok Hoon Lim
OES Faculty Publications

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Nanosecond Pulsed Electric Fields: A New Stimulus to Activate Intracellular Signaling, Stephen J. Beebe, Karl H. Schoenbach
Bioelectrics Publications

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Effect of Humic Substance Photodegradation on Bacterial Growth and Respiration in lake Water, Alexandre M. Anesio, William Granéli, George R. Aiken, David J. Kieber, Kenneth Mopper
Chemistry & Biochemistry Faculty Publications

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2004

Computational Protein Biomarker Prediction: A Case Study for Prostate Cancer, Michael Wagner, Dayanand N. Naik, Alex Pothen, Srinivas Kasukurti, Raghu Ram Devineni, Bao-Ling Adam, O. John Semmes, George L. Wright Jr.
Mathematics & Statistics Faculty Publications

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2003

The Effects of Intense Submicrosecond Electrical Pulses on Cells, Jingdong Deng, Karl H. Schoenbach, E. Stephen Buescher, Pamela S. Hair, Paula M. Fox, Stephen J. Beebe
Bioelectrics Publications

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Comparison of Methods for DNA Isolation from Food Samples for Detection of Shiga Toxin-Producing Escherichia Coli by Real-Time PCR, Loree C. Heller, Carisa R. Davis, K. Kealy Peak, David Wingfield, Andrew C. Cannons, Philip T. Amuso, Jacqueline Cattani
Bioelectrics Publications

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2002

Electrically Mediated Delivery of Vector Plasmid DNA Elicits an Antitumor Effect, L. Heller, D. Coppola
Bioelectrics Publications

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Electric Field Enhanced Plasmid Delivery to Liver Hepatocellular Carcinomas, Richard Gilbert, Mark J. Jaroszeski, Loree Heller, Richard Heller
Bioelectrics Publications

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Effect of Electrically Mediated Intratumor and Intramuscular Delivery of a Plasmid Encoding IFN α on Visible B16 Mouse Melanomas, Loree C. Heller, Stephanie F. Ingram, M. Lee Lucas, Richard A. Gilbert, Richard Heller
Bioelectrics Publications

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IL-12 Plasmid Delivery by in Vivo Electroporation for the Successful Treatment of Established Subcutaneous B16.F10 Melanoma, M. Lee Lucus, Loree Heller, Domenico Coppola, Richard Heller
Bioelectrics Publications

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2000

Electrically Mediated Plasmid DNA Delivery to Hepatocellular Carcinomas in Vivo, L. Heller, M. J. Jaroszeski, D. Coppola, C. Pottinger, R. Gilbert, Richard Heller
Bioelectrics Publications

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1999

Exploring Participation Processes for Technology Development: Case studies of Biotechnology Research and Development Projects in Thailand, Omjai Yuktavetya
Engineering Management & Systems Engineering Theses & Dissertations

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1996

A Computer-Simulated Restriction Fragment Length Polymorphism Analysis of Bacterial Small-Subunit rRNA Genes: Efficacy of Selected Tetrameric Restriction Enzymes for Studies of Microbial Diversity in Nature, Craig L. Moyer, James M. Tiedje, Fred C. Dobbs, David M. Karl
OES Faculty Publications

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1995

Phylogenetic Diversity of the Bacterial Community from a Microbial Mat at an Active, Hydrothermal Vent System, Loihi Seamount, Hawaii, Craig L. Moyer, Fred C. Dobbs, David M. Karl
OES Faculty Publications

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Molecular Cloning and Rare Cleavage Mapping of Human 2P, 6Q, 8Q, 12Q, and 18Q Telomeres, Roberto A. Macina, Ken Morii, Xue-Lan Hu, Dimitri G. Negorev, Chrysanthe Spais, Lisa A. Ruthig, Harold C. Riethman
Medical Diagnostics & Translational Sciences Faculty Publications

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1994

Estimation of Diversity and Community Structure Through Restriction-Fragment-Length-Polymorphism Distribution Analysis of Bacterial 16s Ribosomal-RNA Genes from a Microbial Mat at an Active, Hydrothermal Vent System, Loihi Seamount, Hawaii, Craig L. Moyer, Fred C. Dobbs, David M. Karl
OES Faculty Publications

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1993

A Comparison of NO and N20 Production by the Autophic Nitrifier Nitrosomonas europaea and the Heterotrophic Nitrifier Alcaligenes faecalis, Iris C. Anderson, Mark Poth, Julie Homstead, David J. Burdige
OES Faculty Publications

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1987

Preservation of ATP in Hypersaline Environments, Bruce J. Tuovila, Fred C. Dobbs, Paul A. LaRock, B. Z. Siegel
OES Faculty Publications

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