Applied Physics Letters
Amyloid fibrils are ordered beta-sheet aggregates that are associated with a number of neurodegenerative diseases such as Alzheimer and Parkinson. At present, there is no cure for these progressive and debilitating diseases. Here we report initial studies that indicate that low temperature atmospheric pressure plasma can break amyloid fibrils into smaller units in vitro. The plasma was generated by the plasma pencil, a device capable of emitting a long, low temperature plasma plume/jet. This avenue of research may facilitate the development of a plasma-based medical treatment.
Original Publication Citation
Karakas, E., Munyanyi, A., Greene, L., & Laroussi, M. (2010). Destruction of α -synuclein based amyloid fibrils by a low temperature plasma jet. Applied Physics Letters, 97(143702), 1-3. doi: 10.1063/1.3499277
Karakas, Erdinc; Munyanyi, Agatha; Greene, Lesley; and Laroussi, Mounir, "Destruction of α -Synuclein Based Amyloid Fibrils by a Low Temperature Plasma Jet" (2010). Electrical & Computer Engineering Faculty Publications. 19.