Killing Adherent and Nonadherent Cancer Cells with the Plasma Pencil

Authors

Mounir Laroussi, Old Dominion UniversityFollow
Soheila Mohades, Old Dominion University
Nazir Barekzi, Old Dominion University

Document Type

Article

Publication Date

2015

DOI

10.1116/1.4905666

Publication Title

Biointerphases

Volume

10

Issue

2

Pages

1-7

Abstract

The application of low temperature plasmas in biology and medicine may lead to a paradigm shift in the way various diseases can be treated without serious side effects. Low temperature plasmas generated in gas mixtures that contain oxygen or air produce several chemically reactive species that have important biological implications when they interact with eukaryotic or prokaryotic cells. Here, a review of the effects of low temperature plasma generated by the plasma pencil on different cancerous cells is presented. Results indicate that plasma consistently shows a delayed killing effect that is dose dependent. In addition, there is some evidence that apoptosis is one of the pathways that leads to the death of the cells,indicating that plasma initiates cell signaling pathways.

Original Publication Citation

Laroussi, M., Mohades, S., & Barekzi, N. (2015). Killing adherent and nonadherent cancer cells with the plasma pencil. Biointerphases, 10(2), 029401 (029407 pp.). doi: 10.1116/1.4905666

Repository Citation

Laroussi, Mounir; Mohades, Soheila; and Barekzi, Nazir, "Killing Adherent and Nonadherent Cancer Cells with the Plasma Pencil" (2015). Electrical & Computer Engineering Faculty Publications. 46.
https://digitalcommons.odu.edu/ece_fac_pubs/46