Date of Award
Fall 2010
Document Type
Thesis
Degree Name
Master of Science (MS)
Department
Mechanical & Aerospace Engineering
Program/Concentration
Mechanical Engineering
Committee Director
Julie Zhili Hao
Committee Member
Stephen Knisley
Committee Member
Stacie Ringleb
Call Number for Print
Special Collections; LD4331.E56 J36 2010
Abstract
This thesis presents the design of a novel piezoelectric device with dual functions of studying soft biological tissues. The device consists of a central circular plate and a set of flexural beams. The flexural beams are partially covered with piezoelectric film for integrated transduction. It can function as a force sensor for measuring the mechanical behavior of a tissue sample and a load applier for mimicking physiological loads experienced by the tissue sample in vivo, while the mechanical behavior can be visually observed under a microscope simultaneously. By combining the classic theories in solid mechanics and piezoelectricity, the performance of the piezoelectric device is analyzed. Based on the mechanical behavior obtained from traditional experimental studies on cartilage, the piezoelectric device is designed for studying cartilage. The main application of the device would be; (I) Study the cartilage at cell level (i.e. study of chondrocytes); (2) study the cartilage on tissue level; (3) obtain the relationship between the mechanical stimuli provided and the properties of the natural cartilage and; (4) help in culturing isolated chondrocytes to form artificial cartilage with characteristics close to native cartilage. The results of the device obtained from the theoretical calculations are confirmed using numerical simulation. The fabrication process for the piezoelectric device is also discussed.
Rights
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DOI
10.25776/5b00-dz44
Recommended Citation
Jamadagni, Avin A..
"A Novel Piezoelectric Device with Dual Functions of Studying Biological Soft Tissues"
(2010). Master of Science (MS), Thesis, Mechanical & Aerospace Engineering, Old Dominion University, DOI: 10.25776/5b00-dz44
https://digitalcommons.odu.edu/mae_etds/543