Mathematical and Computer Modelling
Recently, a one-dimensional model was developed which gives a reasonable explanation for the existence of a Critical Size Defect (CSD) in certain animals . In this paper, we examine the more realistic two-dimensional model of a circular wound of uniform depth to see what modifications are to be found, as compared with the one-dimensional model, in studying the CSD phenomenon. It transpires that the range of CSD sizes for a reasonable estimate of parameter values is 1 mm-1 cm. More realistic estimates await the appropriate experimental data.
Original Publication Citation
Arnold, J. S., & Adam, J. A. (1999). A simplified model of wound healing - II: The critical size defect in two dimensions. Mathematical and Computer Modelling, 30(11-12), 47-60. doi:10.1016/s0895-7177(99)00197-1
Arnold, J. S. and Adam, John A., "A Simplified Model of Wound Healing - II: The Critical Size Defect in Two Dimensions" (1999). Mathematics & Statistics Faculty Publications. 94.