Breast Cancer Research
Extracellular matrix proteins from embryonic mesenchyme have a normalizing effect on cancer cells in vitro and slow tumor growth in vivo. This concept is suggestive of a new method for controlling the growth and spread of existing cancer cells in situ and indicates the possibility that extracellular proteins and/or embryonic mesenchymal fibroblasts may represent a fertile subject for study of new anti-cancer treatments.
Original Publication Citation
Bruno, R.D., & Smith, G.H. (2014). A potential mechanism for extracellular matrix induction of breast cancer cell normality. Breast Cancer Research, 16(1), 302-302. doi: 10.1186/bcr3617
Bruno, Robert D. and Smith, Gilbert H., "A Potential Mechanism for Extracellular Matrix Induction of Breast Cancer Cell Normality" (2014). Medical Diagnostics & Translational Sciences Faculty Publications. 13.