Document Type
Article
Publication Date
1995
DOI
10.1101/gr.5.3.225
Publication Title
Genome Research
Volume
5
Issue
3
Pages
225-232
Abstract
Large terminal fragments of human chromosomes 2p, 6q, 8q, 12q, and 18q were cloned using yeast artificial chromosomes (YACs). RecA-assisted restriction endonuclease (RARE) cleavage analysis of genomic DNA samples from 11 unrelated individuals using YAC-derived probes confirmed the telomeric localizations of the half-YACs studied. The cloned Fragments provide telomeric closure of maps for the respective chromosome arms and will supply the reagents needed for analyzing and sequencing these distal subtelomeric regions.
Original Publication Citation
Macina, R.A., Morii, K., Hu, X.L., Negorev, D.G., Spais, C., Ruthig, L.A., & Riethman, H.C. (1995). Molecular cloning and rare cleavage mapping of human 2p, 6q, 8q, 12q, and 18q telomeres. Genome Research, 5(3), 225-232. doi: 10.1101/gr.5.3.225
Repository Citation
Macina, Roberto A.; Morii, Ken; Hu, Xue-Lan; Negorev, Dimitri G.; Spais, Chrysanthe; Ruthig, Lisa A.; and Riethman, Harold C., "Molecular Cloning and Rare Cleavage Mapping of Human 2P, 6Q, 8Q, 12Q, and 18Q Telomeres" (1995). Medical Diagnostics & Translational Sciences Faculty Publications. 39.
https://digitalcommons.odu.edu/medicaldiagnostics_fac_pubs/39
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