Document Type
Article
Publication Date
6-1989
DOI
10.1007/BF01114685
Publication Title
Bioscience Reports
Volume
9
Issue
3
Pages
329-340
Abstract
Several cell surface proteins (Mr = 120,000, 90,000, 63,000 and 47,000) apparently integral to embryonic fibroblast plasma membranes were extracted with detergent and isolated by collagen affinity chromatography. Certain of these proteins (Mr = 120,000, 90,000, and 47,000) were specifically eluted from collagen affinity columns by synthetic peptides containing the amino acid sequence arginyl-glycyl-aspartic acid (RGD). These data show that a number of collagen binding proteins exist on the embryonic fibroblast cell surface. Some of the proteins may be collagen receptors binding to RGD sequences in the collagen molecule while at least one of the proteins (Mr = 63,000) recognizes features other than RGD.
ORCID
0000-0002-4231-9488 (Ogle)
Original Publication Citation
Ogle, R.C., & Little, C.D. (1989). Collagen binding proteins derived from the embryonic fibroblast cell surface recognize arginine-glycine-aspartic acid. Bioscience Reports, 9(3), 329-340. doi: 10.1007/BF01114685
Repository Citation
Ogle, Roy C. and Little, Charles D., "Collagen Binding Proteins Derived from the Embryonic Fibroblast Cell Surface Recognize Arginine-Glycine-Aspartic Acid" (1989). Medical Diagnostics & Translational Sciences Faculty Publications. 7.
https://digitalcommons.odu.edu/medicaldiagnostics_fac_pubs/7
Included in
Amino Acids, Peptides, and Proteins Commons, Cell Biology Commons, Cells Commons, Developmental Biology Commons, Embryonic Structures Commons, Molecular Biology Commons