ORCID

0000-0003-3086-8014 (Qayyum)

Document Type

Article

Publication Date

2025

DOI

10.1093/jscdis/yoaf006

Publication Title

Journal of Sickle Cell Disease

Volume

2

Issue

1

Pages

yoaf006 (1-11)

Abstract

Objectives: Readiness for discharge for a sickle cell disease vaso-occlusive crisis is dictated by factors far beyond pain control, including physical function/activity. We therefore designed and tested a functional status-based pain assessment questionnaire in SCD patients hospitalized with vaso-occlusive crises.

Methods: Sickle cell disease patients on a preselected nursing unit rated 10 draft Functional status-Based Pain Assessment items of activities of daily living on a 5 point Likert scale (0-5) from “very easy” to “very difficult” daily on each day of their admission until discharge, at approximately the same time. Concurrently, they reported Numeric Rating Scale (0-10) pain intensity. For validation, we used exploratory factor analysis, confirmatory factor analysis, and item response theory analysis.

Results and Discussion: We analyzed 503 observations from 175 admissions of 88 patients. Half were female, the mean age was 32.1+/- 11.8 years, and the mean length of stay was 7.1 +/-6.9 days. The mean Numeric Rating Scale (6.8 ± 1.9) was inversely correlated with the mean Functional Status-based Pain Assessment (0-50) score (27 ± 8.0, r= -0.4342, p

Conclusion: The Functional Status-based Pain Assessment shows strong correlation with daily Numeric Rating Scale, is multidimensional, and demonstrates strong construct validity. It may improve assessment of sickle cell disease vaso-occlusive crisis pain and may enhance vaso-occlusive crisis discharge discussions.

Rights

© The Authors 2025.

This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) License, which permits unrestricted reuse, distribution, and re-production in any medium, provided the original work is properly cited.

Data Availability

Article states: "Data used for these analyses are archived at a VCU file storage facility, and may be released, depending on the purpose, upon request of the first (contact) author. Please allow 2-4 weeks for processing time."

Original Publication Citation

Smith, W. R., Qayyum, R., Ulbing, A., Guy, M. S., Sop, D. M., & Zhang, Y. M. (2025). Preliminary validity of a daily functional status pain assessment tool. Journal of Sickle Cell Disease., 2(1), yoaf006. https://doi.org/10.1093/jscdis/yoaf006

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