Document Type
Article
Publication Date
2025
DOI
10.1080/01942638.2024.2449387
Publication Title
Physical & Occupational Therapy in Pediatrics
Volume
Article in Press
Pages
1-30
Abstract
Aim
To assess the effectiveness of family-centered care (FCC) interventions on motor and neurobehavior development of very preterm infants.
Method
Randomized and quasi-randomized trials assessing the effect of FCC on motor and neurobehavioral outcomes in very preterm infants (28–32 wk gestation) were included. Five electronic databases and grey literature were searched from January 2010 to August 2022. Two reviewers independently screened the titles/abstracts and full texts, assessed the risk of bias, and extracted data. The Cochrane Risk of Bias 2.0 Tool and GRADE were used for risk and evidence certainty assessments. Meta-analysis or narrative synthesis was performed based on data availability and heterogeneity.
Results
Seventeen trials with 21 publications were included. GRADE showed low to moderate evidence. At 24 months, FCC interventions improved motor development (Mean Difference (MD):5.00, 95% CI: 2.58–7.42), cognitive development (MD: 3.64, 95% CI: 1.15–6.12), and behavior development (MD: −2.40, 95% CI: −4.32, −0.48) compared to control groups. Further, the FCC showed minimal or inconclusive effects on language, communication, and personal social development measured anytime between newborn and 24 months of age.
Conclusions
Early initiated FCC interventions can be a promising approach to improve motor, cognition, and behavioral development in very preterm infants.
Rights
© 2025 The Authors.
This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.
Data Availability
Article states: "The dataset generated from this review can be requested from the corresponding author."
ORCID
0000-0003-3993-3580 (Khurana)
Original Publication Citation
Raghupathy, M. K., Parsekar, S. S., Nayak, S. R., Karun, K. M., Khurana, S., Spittle, A. J., Lewis, L. E. S., & Rao, B. K. (2025). Effect of family-centered care interventions on motor and neurobehavior development of very preterm infants: A systematic review and meta-analysis. Physical & Occupational Therapy In Pediatrics. Advance online publication. https://doi.org/10.1080/01942638.2024.2449387
Repository Citation
Raghupathy, Manasa Kolibylu; Parsekar, Shradha S.; Nayak, Shubha R.; Karun, Kalesh M.; Khurana, Sonia; Spittle, Alicia J.; Lewis, Leslie Edward S.; and Rao, Bhamini Krishna, "Effect of Family-Centered Care Interventions on Motor and Neurobehavior Development of Very Preterm Infants: A Systematic Review and Meta-Analysis" (2025). Rehabilitation Sciences Faculty Publications. 132.
https://digitalcommons.odu.edu/pt_pubs/132