Synthesis and Characterization of Stable and Purified Silver Nanoparticles (Ag NPs) for Biomedical Applications

Title

Synthesis and Characterization of Stable and Purified Silver Nanoparticles (Ag NPs) for Biomedical Applications

College

College of Sciences

Program

Ph.D. Chemistry

Publication Date

3-28-2019

Abstract

Silver nanoparticles (Ag NPs) have been used for a wide range of applications because of their distinctive optical properties and unique biological effects. These properties highly depend on their sizes, shapes and their surrounding environments. Furthermore, Ag NPs possess high quantum yield of Rayleigh scattering, which enables them to serve as highly sensitive imaging probes and sensors for live cell imaging, as well as assays for sensitive detection of biomarkers for early disease diagnosis. We have successfully synthesized, purified and characterized Ag NPs with average diameters of 2, 12 and 43 nanometer (nm). We have studied the stability of Ag NPs in aqueous solution and cell culture medium, which shows our Ag NPs are stable (non-aggregated) in aqueous solution and given cell culture medium over a long period of time. We have studied their cytotoxic and therapeutic effects on various biological organisms and explored a wide range of their biomedical applications. The detailed experimental designs and updated results will be presented.

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Synthesis and Characterization of Stable and Purified Silver Nanoparticles (Ag NPs) for Biomedical Applications


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