56 - Body Composition Change in Women Treated for Breast Cancer before and 24 months after treatment
Description/Abstract/Artist Statement
Background: Breast cancer (BC) treatments including chemotherapy and radiation can alter body composition leading to significant changes of subcutaneous and visceral adiposity. Increases in fat impact physical health and influence survivorship outcomes such as quality of life and metabolic health. We hypothesized that breast cancer treatment could induce increases in body composition, especially abdominal fats. Objective: Investigate body composition change in women treated for breast cancer before and 24 months after treatment.
Methods: Case-control cohort study design that included 29 BC patients treated with anthracycline chemotherapy and 37 comparators without cancer.To assess body composition, abdominal MRIs were obtained at baseline and 24 months after treatment. A blinded, paired read of the MRIs was performed to assess body fat depots including Subcutaneous (SQ), Intra-Abdominal (IA) divided into Intro-Peritoneal (IP), and Retro-Peritoneal (RP) fat using the SliceOmatic software program. Results: The descriptive statistics are age, weight, height. The study found no significant changes in fat distribution outcomes among breast cancer patients over a 24-month period. The control group also demonstrated consistent fat distribution outcomes over the 24-month period with no significant changes observed in fat measurements (p
The research was funded by NIH grants R01CA19967 and R25HL161607.
Faculty Advisor/Mentor
Greg Hundley, Md
College Affiliation
College of Sciences
Presentation Type
Poster
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56 - Body Composition Change in Women Treated for Breast Cancer before and 24 months after treatment
Background: Breast cancer (BC) treatments including chemotherapy and radiation can alter body composition leading to significant changes of subcutaneous and visceral adiposity. Increases in fat impact physical health and influence survivorship outcomes such as quality of life and metabolic health. We hypothesized that breast cancer treatment could induce increases in body composition, especially abdominal fats. Objective: Investigate body composition change in women treated for breast cancer before and 24 months after treatment.
Methods: Case-control cohort study design that included 29 BC patients treated with anthracycline chemotherapy and 37 comparators without cancer.To assess body composition, abdominal MRIs were obtained at baseline and 24 months after treatment. A blinded, paired read of the MRIs was performed to assess body fat depots including Subcutaneous (SQ), Intra-Abdominal (IA) divided into Intro-Peritoneal (IP), and Retro-Peritoneal (RP) fat using the SliceOmatic software program. Results: The descriptive statistics are age, weight, height. The study found no significant changes in fat distribution outcomes among breast cancer patients over a 24-month period. The control group also demonstrated consistent fat distribution outcomes over the 24-month period with no significant changes observed in fat measurements (p
The research was funded by NIH grants R01CA19967 and R25HL161607.