The Usage of Exercise for Regulating Dopamine and Dopaminergic Terminals for Geriatric Patients with Lewy Body Dementia
Date
April 2020
Description
Lewy Body Dementia (LBD) is a degenerative disease that lowers the quality of life for patients because of the cognitive and movement symptoms. There is no cure for LBD and current medications to reduce symptoms cause side effects. The purpose of this research is to find out how dopamine control can alleviate symptoms in patients with LBD and how increasing certain exercises maybe a possible solution to alleviating LBD patients’ symptoms. Journal articles were gathered for information on how Lewy body aggregates affect the transmission of dopamine, and if exercise could help regulate the transmission. The research showed that decreased dopamine in the basal ganglia and dopamine-dependent functional connectivity in the attention networks contribute to motor and cognition symptoms. There is a possibility that acute aerobic exercise could increase dopamine levels in LBD. I propose that the information overviewed in this review of literature should be applied to future clinical studies.
Presentation Type
Poster
The Usage of Exercise for Regulating Dopamine and Dopaminergic Terminals for Geriatric Patients with Lewy Body Dementia
Lewy Body Dementia (LBD) is a degenerative disease that lowers the quality of life for patients because of the cognitive and movement symptoms. There is no cure for LBD and current medications to reduce symptoms cause side effects. The purpose of this research is to find out how dopamine control can alleviate symptoms in patients with LBD and how increasing certain exercises maybe a possible solution to alleviating LBD patients’ symptoms. Journal articles were gathered for information on how Lewy body aggregates affect the transmission of dopamine, and if exercise could help regulate the transmission. The research showed that decreased dopamine in the basal ganglia and dopamine-dependent functional connectivity in the attention networks contribute to motor and cognition symptoms. There is a possibility that acute aerobic exercise could increase dopamine levels in LBD. I propose that the information overviewed in this review of literature should be applied to future clinical studies.
Comments
This poster based on an individual research project.