Initiation of Action Potential in Murine Ventricular Myocytes by Bursts of Nanosecond Pulses

Authors

Iurii Semenov, Old Dominion University

Document Type

Presentation

Publication Date

2019

Pages

1-31

DOI

10.13140/RG.2.2.20120.65280

Abstract

[First slide] Current situation

I. Among 300,000 persons die from sudden cardiac arrest every year over 40% are victims of fibrillation

II. Defibrillation by an electric shock is the effective therapy against sudden cardiac death

III. Current approach to stop fibrillation may involve disruption of plasma membrane (PM) by an electroporation

IV. Electroporation is damaging, it can: I. Induce post shock arrhythmias II. Complicate patient's recovery III. Lead to death after initially successful resuscitation

Rights

© 2019 The author. All rights reserved.

Included with the kind written permission of the author.

Original Publication Citation

Semenov, I. (2019). Initiation of action potential in murine ventricular myocytes by bursts of nanosecond pulses. Old Dominion University. https://doi.org/10.13140/RG.2.2.20120.65280

Repository Citation

Semenov, Iurii, "Initiation of Action Potential in Murine Ventricular Myocytes by Bursts of Nanosecond Pulses" (2019). Bioelectrics Publications. 385.
https://digitalcommons.odu.edu/bioelectrics_pubs/385

ORCID

0000-0002-0302-1355 (Semenov)