Document Type
Article
Publication Date
6-2010
Publication Title
Biomicrofluidics
Volume
4
Issue
2
Pages
21101
DOI
10.1063/1.3447702
Abstract
Dielectrophoresis (DEP) is employed to differentiate clones of mouse melanoma B16F10 cells. Five clones were tested on microelectrodes. At a specific excitation frequency, clone 1 showed a different DEP response than the other four. Growth rate, melanin content, recovery from cryopreservation, and in vitro invasive studies were performed. Clone 1 is shown to have significantly different melanin content and recovery rate from cryopreservation. This paper reports the ability of DEP to differentiate between two malignant cells of the same origin. Different DEP responses of the two clones could be linked to their melanin content.
Original Publication Citation
Sabuncu, A.C., Liu, J.A., Beebe, S.J., & Beskok, A. (2010). Dielectrophoretic separation of mouse melanoma clones. Biomicrofluidics, 4(2), 021101. doi: 10.1063/1.3447702
Repository Citation
Sabuncu, Ahmet C.; Liu, Jie A.; Beebe, Stephen J.; and Beskok, Ali, "Dielectrophoretic Separation of Mouse Melanoma Clones" (2010). Bioelectrics Publications. 45.
https://digitalcommons.odu.edu/bioelectrics_pubs/45