Document Type

Article

Publication Date

5-2012

DOI

10.4269/ajtmh.2012.11-0342

Publication Title

American Journal of Tropical Medicine and Hygiene

Volume

86

Issue

5

Pages

884-894

Abstract

Temperature has played a critical role in the spatiotemporal dynamics of West Nile virus transmission throughout California from its introduction in 2003 through establishment by 2009. We compared two novel mechanistic measures of transmission risk, the temperature-dependent ratio of virus extrinsic incubation period to the mosquito gonotrophic period (BT), and the fundamental reproductive ratio (R0) based on a mathematical model, to analyze spatiotemporal patterns of receptivity to viral amplification. Maps of BT and R0 were created at 20-km scale and compared throughout California to seroconversions in sentinel chicken flocks at half-month intervals. Overall, estimates of BT and R0 agreed with intensity of transmission measured by the frequency of sentinel chicken seroconversions. Mechanistic measures such as these are important for understanding how temperature affects the spatiotemporal dynamics of West Nile virus transmission and for delineating risk estimates useful to inform vector control agency intervention decisions and communicate outbreak potential.

Original Publication Citation

Hartley, D. M., Barker, C. M., Menach, A. L., Niu, T., Gaff, H. D., & Reisen, W. K. (2012). Effects of temperature on emergence and seasonality of West Nile virus in California. American Journal of Tropical Medicine and Hygiene, 86(5), 884-894. doi:http://dx.doi.org/10.4269/ajtmh.2012.11-0342

ORCID

0000-0002-4034-2684 (Gaff)

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