Document Type

Article

Publication Date

2019

DOI

10.1590/0074-02760180478

Publication Title

Memórias do Instituto Oswaldo Cruz

Volume

114

Pages

e180478 (1-12)

Abstract

The population of Brazil is currently characterised by many individuals harbouring low-intensity Schistosoma mansoni infections. The Kato-Katz technique is the diagnostic method recommended by the World Health Organization (WHO) to assess these infections, but this method is not sensitive enough in the context of low egg excretion. In this regard, potential alternatives are being employed to overcome the limits of the Kato-Katz technique. In the present review, we evaluated the performance of parasitological and immunological approaches adopted in Brazilian areas. Currently, the diagnostic choices involve a combination of strategies, including the utilisation of antibody methods to screen individuals and then subsequent confirmation of positive cases by intensive parasitological investigations.

Rights

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) License.

Original Publication Citation

Silva-Moraes, V., Shollenberger, L. M., Siqueira, L. M. V., Castro-Borges, W., Harn, D. A., Grenfell, R., Rabello, A. L. T., & Coelho, P. M. Z. (2019). Diagnosis of Schistosoma mansoni infections: What are the choices in Brazilian low-endemic areas? Memórias do Instituto Oswaldo Cruz, 114, 1-12, Article e180478. https://doi.org/10.1590/0074-02760180478

ORCID

0000-0002-0943-0838 (Shollenberger)

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