Memórias do Instituto Oswaldo Cruz
The population of Brazil is currently characterised by many individuals harbouring low-intensity Schistosoma mansoni infections. The Kato-Katz technique is the diagnostic method recommended by the World Health Organization (WHO) to assess these infections, but this method is not sensitive enough in the context of low egg excretion. In this regard, potential alternatives are being employed to overcome the limits of the Kato-Katz technique. In the present review, we evaluated the performance of parasitological and immunological approaches adopted in Brazilian areas. Currently, the diagnostic choices involve a combination of strategies, including the utilisation of antibody methods to screen individuals and then subsequent confirmation of positive cases by intensive parasitological investigations.
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Original Publication Citation
Silva-Moraes, V., Shollenberger, L. M., Siqueira, L. M. V., Castro-Borges, W., Harn, D. A., Grenfell, R., Rabello, A. L. T., & Coelho, P. M. Z. (2019). Diagnosis of Schistosoma mansoni infections: What are the choices in Brazilian low-endemic areas? Memórias do Instituto Oswaldo Cruz, 114, 1-12, Article e180478. https://doi.org/10.1590/0074-02760180478
Silva-Moraes, Vanessa; Shollenberger, Lisa M.; Siqueira, Liliane Maria Vidal; Castro-Borges, William; Harn, Donald A.; Grenfell, Rafaella Fortini Queiroz e.; Rabello, Ana Lucia Teles; and Coelho, Paulo Marcos Zech, "Diagnosis of Schistosoma mansoni Infections: What are the Choices in Brazilian Low-Endemic Areas?" (2019). Biological Sciences Faculty Publications. 535.