Document Type
Article
Publication Date
2004
DOI
10.2741/1491
Publication Title
Frontiers in Bioscience
Volume
9
Issue
6
Pages
3399–3433
Abstract
Group A streptococci produce a wide variety of extracellular (cell-associated and released) virulence factors. The function of these factors varies and includes roles in adhesion, spreading, tissue destruction, immune system evasion, and cell toxicity. How these factors are regulated with regard to one another is important for this organism's ability to bring about the variety of diseases this microbe is capable of causing. Therefore, along with the multitude of virulence factors, there are a number of regulatory systems that regulate, either directly or indirectly, the production of these factors and therefore influence the pathogenesis of group A streptococcal infections.
Rights
Article is open access under a Creative Commons CC-BY License (http://creativecommons.org/licenses/by/4.0/)
Original Publication Citation
Hynes, W. (2004). Virulence factors of the group A streptococci and genes that regulate their expression. Frontiers in Bioscience, 9(6), 3399-3433. https://doi.org/10.2741/1491
Repository Citation
Hines, Wayne, "Virulence Factors of the Group A Streptococci and Genes that Regulate Their Expression" (2004). Biological Sciences Faculty Publications. 684.
https://digitalcommons.odu.edu/biology_fac_pubs/684