Reply to: S. N. Katkuri et al. and H. Liu et al. on Early and Sustained Improvements in Sense of Smell with Tezepelumab Treatment in Patients with Chronic Rhinosinusitis with Nasal Polyps (WAYPOINT)

Authors

• Joaquim Mullol, University of Barcelona
• Joseph K. Han, Macon & Joan Brock Virginia Health Sciences at Old Dominion UniversityFollow
• Tanya M. Laidlaw, Harvard Medical School
• Claire Hopkins, Guy's and St. Thomas' Hospital, London, U. K.
• Anju T. Peters, Northwestern University
• Oliver Pfaar, Phillips University of Marburg
• Martin Desrosiers, University of Montreal
• Stella E. Lee, Harvard Medical School
• Andrew P. Lane, Johns Hopkins School of Medicine
• Claudia Chen, BioPharmaceuticals Medical
• Yun Chon, Thousand Oaks, California
• Sandhia S. Ponnarambil, AstraZeneca, Cambridge, UK
• Andrew Foster, AstraZeneca, Gaithersburg, Maryland
• Andrew W. Lindsley, US Medical Affairs, Thousand Oaks, California
• Christopher S. Ambrose, AstraZeneca, Gaithersburg, Maryland

Document Type

Article

Publication Date

2026

DOI

10.1002/alr.70168

Publication Title

International Forum of Allergy & Rhinology

Volume

16

Issue

5

Pages

534-536

Abstract

[Introduction] We thank Dr. S. N. Katkuri, Dr. H. Liu, and their coauthors [1, 2] for their interest in our recent publication describing the improvements in loss of smell symptoms with tezepelumab versus placebo in patients with uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP) in the WAYPOINT trial (NCT04851964) [3]. We are grateful for the authors' feedback on the clinical significance of the data presented and their appreciation of the consistency observed across a range of baseline clinical characteristic and demographic subgroups.

Rights

© 2026 ARS-AAOA, LLC.

Published under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) License.

Original Publication Citation

Mullol, J., Han, J. K., Laidlaw, T. M., Hopkins, C., Peters, A. T., Pfaar, O., Desrosiers, M., Lee, S. E., Lane, A. P., Chen, C., Chon, Y., Ponnarambil, S. S., Foster, A., Lindsley, A. W., & Ambrose, C. S. (2026). Reply to: S. N. Katkuri et al. And H. Liu et al. On early and sustained improvements in sense of smell with tezepelumab treatment in patients with chronic rhinosinusitis with nasal polyps (WAYPOINT). International Forum of Allergy & Rhinology, 16(5), 534-536. https://doi.org/10.1002/alr.70168

Repository Citation

Mullol, J., Han, J. K., Laidlaw, T. M., Hopkins, C., Peters, A. T., Pfaar, O., Desrosiers, M., Lee, S. E., Lane, A. P., Chen, C., Chon, Y., Ponnarambil, S. S., Foster, A., Lindsley, A. W., & Ambrose, C. S. (2026). Reply to: S. N. Katkuri et al. And H. Liu et al. On early and sustained improvements in sense of smell with tezepelumab treatment in patients with chronic rhinosinusitis with nasal polyps (WAYPOINT). International Forum of Allergy & Rhinology, 16(5), 534-536. https://doi.org/10.1002/alr.70168