Short-Term Removal of Exercise Impairs Flow-Mediated Dilation Similarly in Older and Younger Adults
College
College of Health Sciences
Department
Rehabilitation Sciences
Graduate Level
Doctoral
Graduate Program/Concentration
Kinesiology and Rehabilitation
Presentation Type
No Preference
Abstract
AIMS: To investigate and compare the effects of 5 days of removal of exercise on endothelial function in older and younger active adults. METHODS: Older (n=12, 63.8±2.2 years) and younger (n=12, 23.9±0.7 years) active (≥90 min/week of exercise) adults underwent 7 days of habitual exercise (EX) and 5 days of removal of exercise (NOEX). Endothelial function was assessed via brachial and popliteal artery flow-mediated dilation (FMD) on the day following the EX-phase and on days 3 and 5 of the NOEX-phase. RESULTS: Steps per day were reduced in both older (EX: 6,687.9±639.3; NOEX: 3,155.3±364.6; ppp=0.035) and peak diameter (Old: EX: 4.02 ± 0.18cm; NOEX: 3.97 ± 0.17cm; Young: EX: 4.40 ± 0.14cm; NOEX: 4.28 ± 0.15cm; pp>0.05), although a significant interaction was observed for time x age (pp=0.014) and peak diameter (Old: EX 5.74 ± 0.37cm; NOEX: 5.62 ± 0.38cm; Young: EX: 6.07 ± 0.27cm; NOEX: 5.92 ± 0.26cm; pp>0.05). CONCLUSIONS: Older and younger active subjects experience similar impairments in brachial and popliteal artery FMD following short-term (5 days) removal of exercise.
Keywords
Endothelial function, inactivity, cardiometabolic.
Short-Term Removal of Exercise Impairs Flow-Mediated Dilation Similarly in Older and Younger Adults
AIMS: To investigate and compare the effects of 5 days of removal of exercise on endothelial function in older and younger active adults. METHODS: Older (n=12, 63.8±2.2 years) and younger (n=12, 23.9±0.7 years) active (≥90 min/week of exercise) adults underwent 7 days of habitual exercise (EX) and 5 days of removal of exercise (NOEX). Endothelial function was assessed via brachial and popliteal artery flow-mediated dilation (FMD) on the day following the EX-phase and on days 3 and 5 of the NOEX-phase. RESULTS: Steps per day were reduced in both older (EX: 6,687.9±639.3; NOEX: 3,155.3±364.6; ppp=0.035) and peak diameter (Old: EX: 4.02 ± 0.18cm; NOEX: 3.97 ± 0.17cm; Young: EX: 4.40 ± 0.14cm; NOEX: 4.28 ± 0.15cm; pp>0.05), although a significant interaction was observed for time x age (pp=0.014) and peak diameter (Old: EX 5.74 ± 0.37cm; NOEX: 5.62 ± 0.38cm; Young: EX: 6.07 ± 0.27cm; NOEX: 5.92 ± 0.26cm; pp>0.05). CONCLUSIONS: Older and younger active subjects experience similar impairments in brachial and popliteal artery FMD following short-term (5 days) removal of exercise.