Persistent Peristomal Pain Due to an Exposed Cutaneous Nerve

Authors

• Iain Noel Encarnacion, Macon & Joan Brock Virginia Health Sciences at Old Dominion University
• Kaylin Beiter, Perelman School of Medicine at the University of Pennsylvania
• Natasha Hakkal, Perelman School of Medicine at the University of Pennsylvania
• Emily Hejazi, Perelman School of Medicine at the University of Pennsylvania
• Paul Hernandez, Perelman School of Medicine at the University of Pennsylvania
• Melissa Laughter, Perelman School of Medicine at the University of Pennsylvania
• Shannon Nugent, Perelman School of Medicine at the University of Pennsylvania
• Samir Thaker, Perelman School of Medicine at the University of Pennsylvania
• Xiaowei Xu, Perelman School of Medicine at the University of Pennsylvania
• Misha Rosenbach, Perelman School of Medicine at the University of Pennsylvania

ORCID

0009-0006-4972-7093 (Encarnacion)

Document Type

Article

Publication Date

2026

DOI

10.1016/j.jdcr.2026.02.013

Publication Title

JAAD Case Reports

Volume

70

Pages

172-174

Abstract

[Introduction]

Case description

A 25-year-old woman with a history of ulcerative colitis treated with multiple abdominal surgeries complicated by peristomal pyoderma gangrenosum (PPG) presented with severe peristomal pain and ulceration. Treatment course was complicated; disease control was achieved via combination infliximab 10 mg/kg every 4 weeks, corticosteroids (topical triamcinolone 0.1% ointment, intralesional 10 mg/ml injections, and oral prednisone 30 mg daily with a gradual taper), and cyclosporine 125 mg tapering by 25 mg every 3 weeks, ultimately tapered to infliximab monotherapy.

Rights

© 2026 The Authors

This is an open access article under the Creative Commons Attribution 4.0 International (CC BY 4.0) License.

Original Publication Citation

Encarnacion, I. N., Beiter, K., Hakkal, N., Hejazi, E., Hernandez, P., Laughter, M., Nugent, S., Thaker, S., Xu, X., & Rosenbach, M. (2026). Persistent peristomal pain due to an exposed cutaneous nerve. JAAD Case Reports, 70, 172-174. https://doi.org/10.1016/j.jdcr.2026.02.013

Repository Citation

Encarnacion, I. N., Beiter, K., Hakkal, N., Hejazi, E., Hernandez, P., Laughter, M., Nugent, S., Thaker, S., Xu, X., & Rosenbach, M. (2026). Persistent peristomal pain due to an exposed cutaneous nerve. JAAD Case Reports, 70, 172-174. https://doi.org/10.1016/j.jdcr.2026.02.013