Date of Award
Summer 2015
Document Type
Dissertation
Degree Name
Doctor of Philosophy (PhD)
Department
Psychology
Committee Director
Serina A. Neumann
Committee Member
Paul A. Sayegh
Committee Member
Michael L. Stutts
Committee Member
Richard W. Handel
Committee Member
Desideria S. Hacker
Abstract
Posttraumatic Stress Disorder (PTSD) is a commonly occurring mental health diagnosis, and is particularly prevalent in combat veterans. Although there has been some success treating PTSD with various forms of therapy, many cases remain refractory to the current standard of care. This pilot study combines transcranial magnetic stimulation (TMS) to the right dorsolateral prefrontal cortex (DLPFC) and the supplementary motor area (SMA) with a standardized exposure protocol for the treatment of chronic, treatment-resistant PTSD. The aims are to (1) determine if the treatment is safe and well tolerated, (2) determine if PTSD and concomitant depression and anxiety symptoms improve, and (3) determine if executive functioning and memory improve. Results indicated the treatment was safe and well tolerated, and improvements were seen across psychological symptoms. Neurocognitively, improvements were seen in executive functioning but not in non-executive memory. Statistically significant results must be interpreted with caution due to the likelihood of sampling error associated with a small sample size. However, clinical results were striking, with six of the seven participants no longer meeting criteria for PTSD by the end of the study. Clinical results for this pilot study were promising and warrant further investigation with larger sample sizes utilizing a RCT model to confirm and expand upon these preliminary findings.
Rights
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DOI
10.25777/fk5g-sw84
ISBN
9781339109619
Recommended Citation
Seagly, Katharine.
"PTSD Symptom Severity and Neurocognitive Performance as a Function of Combined TMS and Imaginal Exposure in OIF/OEF Combat Veterans with Treatment Resistant PTSD"
(2015). Doctor of Philosophy (PhD), Dissertation, Psychology, Old Dominion University, DOI: 10.25777/fk5g-sw84
https://digitalcommons.odu.edu/psychology_etds/11
Comments
The VIRGINIA CONSORTIUM PROGRAM IN CLINICAL PSYCHOLOGY is a joint program of Eastern Virginia Medical School, Norfolk State University, and Old Dominion University.