Document Type

Article

Publication Date

2010

DOI

10.3390/ijerph7082988

Publication Title

International Journal of Environmental Research and Public Health

Volume

7

Issue

7

Pages

2988-3005

Abstract

Recent evidence suggests that endocrine disrupting chemicals (EDCs) may cause perturbations in endogenous hormonal regulation that predispose to weight gain. Using data from NHANES (1999-2002), we investigated the association between body mass index (BMI), waist circumference (WC) and selected persistent organic pollutants (POPs) via multiple linear regressions. Consistent interaction was found between gender, ln oxychlordane and ln p,p' DDT. Also, we found an association between WC and ln oxychlordane and ln hpcdd in subjects with detectable levels of POPs, whereas an association between WC and ln p,p' DDT was observed in all subjects. Furthermore, ln Ocdd showed an increase with higher WC and BMI, whereas, ln trans-nonachlor decreased with higher BMI. Hence, BMI and WC are associated with POPs levels, making the chemicals plausible contributors to the obesity epidemic.

Original Publication Citation

Elobeid, M.A., Padilla, M.A., Brock, D.W., Ruden, D.M., & Allison, D.B. (2010). Endocrine disruptors and obesity: An examination of selected persistent organic pollutants in the NHANES 1999-2002 data. International Journal of Environmental Research and Public Health, 7(7), 2988-3005. doi: 10.3390/ijerph7082988

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