Description/Abstract/Artist Statement

Purpose: Several orofacial symptoms of Lyme disease can affect anatomical structures of the head and neck which are frequently examined by dental professionals. The purpose of this systematic review was to examine the literature to identify the frequencies of orofacial manifestations documented in U.S. populations with Lyme disease.

Methods: Four electronic databases (Dentistry and Oral Sciences, PubMed, Cinahl Plus, and Medline) were systematically searched from May 2019 until October 2019 using keywords and MeSH terms to identify relevant studies. The review followed guidelines set forth in Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). A modified version of the Cochrane Data Collection Form for Randomized Control Trials and Non-randomized Control Trials was used to asses quality.

Results: An initial search extracted 217,381 articles; 43 met inclusion/exclusion criteria and were reviewed for quality. Twelve articles published from 1992-2017 were deemed appropriate for inclusion in the systematic review. All were from non-dental journals and represented mostly male populations from less than half (n=6) of the endemic states. A total of eight orofacial manifestations occurring within head/neck regions often examined by dental professionals were documented: headache (n=11, 92%), facial palsy (n=11, 92%), temporomandibular joint arthralgia (n=2, 17%), altered taste (n=1, 8%), stiff neck (n=4, 33%), sore throat (n=1, 8%), neck pain/arthralgia (n=5, 42%), and erythema migrans rash (n=1, 8%).

Conclusion: Current research regarding orofacial manifestations of Lyme disease is needed so that this medical phenomenon can be well understood by dental professionals in order to best serve their patients.

Presenting Author Name/s

Kelsey Jones

Faculty Advisor/Mentor

Holly Gaff

Presentation Type

Oral Presentation

Disciplines

Life Sciences

Session Title

College of Sciences 1

Location

Learning Commons @ Perry Library Conference Room 1310

Start Date

2-8-2020 9:00 AM

End Date

2-8-2020 10:00 AM

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Feb 8th, 9:00 AM Feb 8th, 10:00 AM

Orofacial Manifestations of Lyme Disease: A Systematic Review

Learning Commons @ Perry Library Conference Room 1310

Purpose: Several orofacial symptoms of Lyme disease can affect anatomical structures of the head and neck which are frequently examined by dental professionals. The purpose of this systematic review was to examine the literature to identify the frequencies of orofacial manifestations documented in U.S. populations with Lyme disease.

Methods: Four electronic databases (Dentistry and Oral Sciences, PubMed, Cinahl Plus, and Medline) were systematically searched from May 2019 until October 2019 using keywords and MeSH terms to identify relevant studies. The review followed guidelines set forth in Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). A modified version of the Cochrane Data Collection Form for Randomized Control Trials and Non-randomized Control Trials was used to asses quality.

Results: An initial search extracted 217,381 articles; 43 met inclusion/exclusion criteria and were reviewed for quality. Twelve articles published from 1992-2017 were deemed appropriate for inclusion in the systematic review. All were from non-dental journals and represented mostly male populations from less than half (n=6) of the endemic states. A total of eight orofacial manifestations occurring within head/neck regions often examined by dental professionals were documented: headache (n=11, 92%), facial palsy (n=11, 92%), temporomandibular joint arthralgia (n=2, 17%), altered taste (n=1, 8%), stiff neck (n=4, 33%), sore throat (n=1, 8%), neck pain/arthralgia (n=5, 42%), and erythema migrans rash (n=1, 8%).

Conclusion: Current research regarding orofacial manifestations of Lyme disease is needed so that this medical phenomenon can be well understood by dental professionals in order to best serve their patients.