Document Type

Article

Publication Date

2025

DOI

10.3390/bios15090578

Publication Title

Biosensors

Volume

15

Issue

9

Pages

578

Abstract

Motion artifacts (MA) cause great variability in a measured arterial pulse signal, and treatment of MA solely as a baseline drift (BD) fails to eliminate its effect on the measured signal. This paper presents a study on the effect of MA at rest (< 0.7 Hz) on measured arterial pulse signals using a microfluidic-based tactile sensor. By taking full account of the dynamic behavior of the transmission path from the true pulse signal in an artery to a measured pulse signal at the sensor, the tissue-contact-sensor (TCS) stack, an analytical model of MA in a measured pulse signal is developed. In this model, the TCS stack is treated as a 1DOF system for its dynamic behavior; MA is quantified as the displacement (i.e., BD) and time-varying system parameters (TVSP) of the TCS stack. The mathematical expression of MA in a measured pulse signal reveals that while BD remains as low-frequency additive noise, TVSP causes time-varying harmonics in a measured pulse signal. Further time-frequency analysis (TFA) of measured pulse signals validates the existence of TVSP and, for the first time, reveals its effect on a measured pulse signal: time-varying amplitude in each harmonic and non-flat harmonic-MA-coupled baseline.

Rights

© 2025 by the authors.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International (CC BY 4.0) License.

Data Availability

Article states: "The data that support the findings of this study are available upon reasonable request from the corresponding author. The data are not publicly available due to privacy and ethical restrictions."

Original Publication Citation

Rahman, M. M., Hasan, M., & Hao, Z. (2025). Motion artifacts (MA) at-rest in measured arterial pulse signals: Time-varying amplitude in each harmonic and non-flat harmonic-MA-coupled baseline. Biosensors, 15(9), Article 578. https://doi.org/10.3390/bios15090578

ORCID

0000-0001-8405-2227 (Rahman), 0009-0006-7544-5938 (Hasan), 0000-0003-2024-1947 (Hao)

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