The Impact of Physical Activity on Polychlorinated Biphenyls in Pregnant Women

Description/Abstract/Artist Statement

Polychlorinated Biphenyls (PCBs) have numerous deleterious effects on pregnant women and their fetus/offspring when exposed in utero. Physical activity has positive health outcomes on pregnant women and offspring. However, studies are lacking on whether physical activity impacts serum PCB levels in pregnant women. This secondary data analysis of the 1994-2004 National Health and Nutrition Examination Survey examined if participating in moderate and vigorous physical activity, as assessed by questionnaire, in 181 pregnant women, impacted PCB levels. Lipid-adjusted PCB 138, 153, and 180 were assessed and related covariates (age, weight change over the previous year, and body mass index (BMI)) were determined. 32 and 82 individuals reported participating in vigorous and moderate physical activity, respectively. PCB 138, 153, and 180 were significantly higher in those who reported participating in vigorous activity (Vig) compared to no vigorous (NoVig) activity (PCB 138:Vig-13.83±0.91, NoVig-11.48±0.72 ng/g, p=0.02; PCB153: Vig-21.06±3.31, NoVig-15.20±1.14 ng/g, p=0.02; PCB 180: Vig-13.26±2.31, NoVig-8.62±0.71ng/g, p=0.06). PCB 138, 153, and 180 were not significantly different in those who reported participating in moderate activity (Mod) compared to no moderate activity (NoMod) (PCB 138: Mod-12.53±0.97, NoMod-11.24±1.14 ng/g, p=0.42; PCB153: Mod-17.35±1.78, NoMod-15.04±1.67 ng/g, p=0.38; PCB 180: Mod-10.26±1.20, NoMod-8.55±1.13 ng/g, p=0.33). After adjusting for age, weight change status, and BMI, PCB levels for both vigorous and moderate activity status were not statistically significant (p>0.05). Vigorous, but not moderate physical activity may be a better predictor of elevated PCB levels in pregnant women; however, after adjusting for relevant covariates this significance no longer remains.

Presenting Author Name/s

Ashley Middleton

Faculty Advisor/Mentor

Leryn Reynolds, Joel Harden

Faculty Advisor/Mentor Department

Human Movement Sciences Department

College Affiliation

College of Education & Professional Studies (Darden)

Presentation Type

Oral Presentation

Disciplines

Physiology | Public Health

Session Title

Colleges of Business, Education, Engineering Presentations

Location

Learning Commons @Perry Library, Room 1310

Start Date

3-25-2023 9:30 AM

End Date

3-25-2023 10:30 AM

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Mar 25th, 9:30 AM Mar 25th, 10:30 AM

The Impact of Physical Activity on Polychlorinated Biphenyls in Pregnant Women

Learning Commons @Perry Library, Room 1310

Polychlorinated Biphenyls (PCBs) have numerous deleterious effects on pregnant women and their fetus/offspring when exposed in utero. Physical activity has positive health outcomes on pregnant women and offspring. However, studies are lacking on whether physical activity impacts serum PCB levels in pregnant women. This secondary data analysis of the 1994-2004 National Health and Nutrition Examination Survey examined if participating in moderate and vigorous physical activity, as assessed by questionnaire, in 181 pregnant women, impacted PCB levels. Lipid-adjusted PCB 138, 153, and 180 were assessed and related covariates (age, weight change over the previous year, and body mass index (BMI)) were determined. 32 and 82 individuals reported participating in vigorous and moderate physical activity, respectively. PCB 138, 153, and 180 were significantly higher in those who reported participating in vigorous activity (Vig) compared to no vigorous (NoVig) activity (PCB 138:Vig-13.83±0.91, NoVig-11.48±0.72 ng/g, p=0.02; PCB153: Vig-21.06±3.31, NoVig-15.20±1.14 ng/g, p=0.02; PCB 180: Vig-13.26±2.31, NoVig-8.62±0.71ng/g, p=0.06). PCB 138, 153, and 180 were not significantly different in those who reported participating in moderate activity (Mod) compared to no moderate activity (NoMod) (PCB 138: Mod-12.53±0.97, NoMod-11.24±1.14 ng/g, p=0.42; PCB153: Mod-17.35±1.78, NoMod-15.04±1.67 ng/g, p=0.38; PCB 180: Mod-10.26±1.20, NoMod-8.55±1.13 ng/g, p=0.33). After adjusting for age, weight change status, and BMI, PCB levels for both vigorous and moderate activity status were not statistically significant (p>0.05). Vigorous, but not moderate physical activity may be a better predictor of elevated PCB levels in pregnant women; however, after adjusting for relevant covariates this significance no longer remains.