Evaluating the Effect of Biomaterials on Electric Field in a Nanosecond Pulsed Helium Plasma Jet
Document Type
Abstract
Publication Date
11-7-2024
DOI
10.25776/4r48-mk28
Abstract
Nonthermal atmospheric pressure plasma jet (APPJ) is a promising method for medical applications such as sterilization, wound healing, cancer treatment, and materials processing. It produces reactive plasma agents including reactive oxygen species (ROS), charged particles, electric field, and UV photons, which are known to play crucial roles. When an APPJ impinges on a biomaterial, the property of the biomaterial may influence the formation of the plasma and the associated chemistry, resulting in different ROS productions [1,2]. In addition, the distribution and temporal development of the electric field in the ns-APPJ may also be impacted. In this study, we compared the electric field of a helium ns-APPJ, powered by 200 ns, 7 kV pulses at 1 kHz, impinging on ultrapure water, phosphate-buffered saline solution (PBS), and pigskin. Utilizing the electric field-induced second harmonic (E-FISH) method enabled by a femtosecond laser, a cylindrical lens for beam-shaping, and a gated intensified charge-coupled device (ICCD), the absolute electric field on the order of tens of kV/cm was observed. It was the strongest near the needle tip, with PBS inducing the highest electric field. The effects of biomaterial property on the electrode configuration, the ionization wave propagation, and hence the electric field in the plasma are discussed.
[1] E.A Oshin, M.Z. Rahman, and C. Jiang “Effect of water conductivity on a guided streamer and the ROS production in liquid.” Journal of Physics D: Applied Physics, In submission.
[2] M. Lai, et al. “The production of OH in a nanosecond pulsed helium plasma jet impinging on water, saline, or pigskin” Journal of Applied Physics, 131(17) (2022)
Repository Citation
Oshin, Edwin A.; Dogariu, Arthur; and Jiang, Chunqi, "Evaluating the Effect of Biomaterials on Electric Field in a Nanosecond Pulsed Helium Plasma Jet" (2024). 2024 Frank Reidy Research Center for Bioelectrics Retreat. 6.
https://digitalcommons.odu.edu/bioelectrics-2024retreat/6
Comments
* This material is based upon work supported in part by the U.S. Air Force Office of Scientific Research (AFOSR) under award number FA9550-22-1-0428, and by the U.S. Department of Energy, Office of Science, Office of Fusion Energy Sciences under award numbers DE-SC0024627 and DE-SC0024623.