Date of Award
Summer 1983
Document Type
Thesis
Degree Name
Master of Science (MS)
Department
Chemistry & Biochemistry
Program/Concentration
Chemistry
Committee Director
Patricia A. Pleban
Committee Member
John D. Van Norman
Committee Member
Billy T. Upchurch
Committee Member
Blair Chrenka
Call Number for Print
Special Collections LD4331.C45L43
Abstract
The purpose of this research project was to develop assay procedures for determination of zinc in erythrocytes. Three methodologies were developed. The methods were evaluated on the basis of within-run and between-run precision. The most reproducible method, the 213.856 nm flame methodology, was used to determine red blood cell zinc concentrations in more than 200 samples obtained from the Neonatal Intensive care Unit at the Children's Hospital of the King's Daughters.
This study demonstrated that erythrocyte zinc levels in premature infants were similar to those of healthy adults. A linear relation between plasma and red blood cell zinc concentrations was investigated. None was found. Gestational age was correlated with both plasma and erythrocyte zinc levels. While a slight relationship was shown for red blood cells, no conclusion could be drawn as to the relationship between plasma zinc concentrations and gestational age. Neither the erythrocyte nor the plasma zinc levels for the groups could be correlated to zinc supplementation. This finding was in agreement with findings of other researchers.
Rights
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DOI
10.25777/fpzk-ge11
Recommended Citation
Lewis, Tanya M..
"Determination of Erythrocyte Zinc Concentrations Using Zeeman Effect Atomic Absorption Spectroscopy"
(1983). Master of Science (MS), Thesis, Chemistry & Biochemistry, Old Dominion University, DOI: 10.25777/fpzk-ge11
https://digitalcommons.odu.edu/chemistry_etds/130