Document Type
Article
Publication Date
2023
DOI
10.14814/phy2.15591
Publication Title
Physiological Reports
Volume
11
Issue
2
Pages
e15591 (1-12)
Abstract
Postprandial glycemia (PPG) predicts cardiovascular disease, and short-term physical inactivity increases PPG in young, active adults. Whether this occurs in older, active adults who may be more prone to bouts of inactivity is unknown. This study determined if postprandial interstitial glucose (PPIG) was impaired in active older adults following the removal of exercise for 3 days (NOEX) compared to active young adults. In this randomized, crossover study, 11 older (69.1 ± 1.9 years) and 9 young (32.8 ± 1.8 years) habitually active (≥90 min/week of exercise) adults completed 3-days of NOEX and 3-days of normal habitual exercise (EX), separated by ≥1 week. Diet was standardized across phases. Glycemic control (3-day average) was assessed via continuous glucose monitoring during both phases. Significant main effects of age and phase were detected (p < 0.05), but no interaction was found for steps/day (p > 0.05) (old EX: 6283 ± 607, old NOEX: 2380 ± 382 and young EX: 8798 ± 623, young NOEX: 4075 ± 516 steps/day). Significant main effects of age (p = 0.002) and time (p < 0.001) existed for 1-h PPIG, but no effect of phase or interactions was found (p > 0.05). Significant main effects (p < 0.05) of age (old: 114 ± 1 mg/dl, young: 106 ± 1 mg/dl), phase (NOEX: 112 ± 1 mg/dl, EX: 108 ± 1 mg/dl), and time (0 min: 100 ± 2, 30 min: 118 ± 2, 60 min: 116 ± 2, 90 min: 111 ± 2, 120 min: 108 ± 2 mg/dl) in 2-h PPIG were detected, but no interaction was found (p > 0.05). However, only significant main effects of phase (NOEX: 14 ± 1 and EX:12 ± 1, p > 0.05) were found for 24-h blood glucose standard deviation. Older adults appear to have impaired glycemic control compared to young adults and exercise removal impairs glycemic control in both populations. Yet, the impairment in glycemic control with exercise removal is not different between old and young adults.
Rights
© 2023 The Authors.
This is an open access article under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Original Publication Citation
Reynolds, L. J., Williams, T. M., Harden, J. E., Twiddy, H. M., & Kearney, M. L. (2023). Short-term removal of exercise impairs glycemic control in older adults: A randomized trial. Physiological Reports, 11(2), 1-12, Article e15591. https://doi.org/10.14814/phy2.15591
ORCID
0000-0003-0075-2168 (Reynolds)
Repository Citation
Reynolds, Leryn J.; Williams, Troy M.; Harden, Joel E.; Twiddy, Hannah M.; and Kearney, Monica L., "Short-Term Removal of Exercise Impairs Glycemic Control in Older Adults: A Randomized Trial" (2023). Human Movement Studies & Special Education Faculty Publications. 137.
https://digitalcommons.odu.edu/hms_fac_pubs/137
Included in
Cardiology Commons, Cardiovascular System Commons, Endocrinology, Diabetes, and Metabolism Commons, Exercise Science Commons