Theses and dissertations published by graduate students in the Department of Chemistry and Biochemistry, College of Sciences, Old Dominion University, since Fall 2016 are available in this collection. Backfiles of all dissertations (and some theses) have also been added.

In late Fall 2023 or Spring 2024, all theses will be digitized and available here. In the meantime, consult the Library Catalog to find older items in print.

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Theses/Dissertations from 2023

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Dissertation: Structural Insights into the cl-Par-4 Protein: Ionic Requirements, Conformational Transitions, and Interaction With Cisplatin, Krishna Kumar Raut

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Thesis: Synthesis and Characterization of Cobalt(III) Complexes and a Vanadium(IV) Complex with Flavonoids as Ligands, Ethan Schroeder

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Thesis: Molecular Evidence for the Export of Terrigenous Organic Matter to the North Gulf of Mexico by Solid-State 13C NMR and Fourier Transform Ion Cyclotron Resonance Mass Spectrometry of Humic Acids, Sarah Ann Ware

Theses/Dissertations from 2022

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Dissertation: Investigating the Biorisk of Genetically Engineered Thermosynechococcus Elongatus BP1, Cherrelle Leah Barnes

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Dissertation: Implications of Metal Coordination in Damage and Recognition of Nucleic Acids and Lipid Bilayers, Ana Dreab

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Dissertation: Clostridioides Difficile Biofilm and Spore Production in Response to Antibiotics and Immune Stress, Adenrele M. Oludiran

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Dissertation: Design, Synthesis and Characterization of Triazole Based Glycoconjugates and 4,6-Acetal Protected D-Glucosamine Derivatives as Low Molecular Weight Gelators, Pooja Sharma

Theses/Dissertations from 2021

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Dissertation: Design, Synthesis and Characterization of Carbohydrate Based Macrocycles, Photo Responsive Derivatives, and Glycoconjugates Based Low Molecular Weight Gelators, Surya Bahadur Adhikari

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Dissertation: Computational and Experimental Investigation into the Determinants of Protein Structure, Folding, and Stability in the β-Grasp Superfamily, John T. Bedford II

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Dissertation: Synthesis and Characterization of 4,6-protected Glucosamine Derivatives and Branched Glycoconjugates, Jonathan Bietsch

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Dissertation: Biophysical Characterization of the Par-4 Tumor Suppressor: Evidence of Structure Outside the Coiled Coil Domain and Interactions with Platinum Chemotherapeutics, Andrea Megan Clark

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Dissertation: Computational Analysis of Type 3 Iodothyronine Deiodinase: Potential Inhibitors, Substrate Binding, and Dimer Structure, Eric Scott Marsan

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Dissertation: The Development of Novel Carbohydrate-Based Gelators and Their Applications as Advanced Soft Materials, Joedian Morris

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Dissertation: Genetically Engineered Thermosynechococcus Elongatus BP1: Assessment of Potential Biorisks and Biofuel Production, Thu Ho Anh Nguyen-Jones

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Dissertation: Evaluating the Role of the Stringent Response Mechanism in Clostridioides difficile Survival and Pathogenesis, Astha Pokhrel

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Dissertation: Mechanisms of Stress Survival in Gram Positive Bacterial Pathogens, Asia Poudel

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Dissertation: Improvement of Biochar Through Ozonization and Biosafety of Genetically Engineered Cyanobacteria, Oumar Sacko

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Thesis: Evaluation of Horizontal Gene Transfer Between Genetically Engineered Cyanobacteria and Gram-Negative Bacteria, Andriana Chrysovalanti Zourou

Theses/Dissertations from 2020

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Dissertation: Synthesis, Characterization, and Kinetics Studies of New Cobalt Complexes for the Production of H2 in Acidic Media, Michael John Celestine

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Dissertation: Structural Characterization of Organic Matter in Oil Shales Using Multiple Nuclear Magnetic Resonance Spectroscopic Techniques, Wenying Chu

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Dissertation: Advances in the Understanding of Sourcing and Fate of Pyrogenic Organic Matter in the Environment, Aleksandar Ivaylov Goranov

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Dissertation: Synthesis, Characterization, Spectroscopic, and Mesomorphic Studies of New Schiff Base Ligands and Titanium, Cobalt, Nickel and Copper Metal Centers, Raj K. Gurung

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Thesis: Network Approaches to Elucidate the Determinants of Protein Topology and Stability, Zeinab Haratipour

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Dissertation: Lignin: A Likely Precursor of a Significant Fraction of Humic Substances Via Oxidative Transformations, Seyyedhadi Khatami

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Dissertation: Synthesis and Characterization of Carbohydrate Based Molecular Gelators and Macrocycles Through Cycloaddition Reactions, Dan Wang

Theses/Dissertations from 2019

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Dissertation: Synthesis, Characterization, and Drug Delivery Applications of Carbohydrate Based Low Molecular Weight Gelators, Kristen Elizabeth Bashaw

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Thesis: A Dual Nanostructured Approach to SERS Amenable to Large-Scale Production, Kory Brian Castro

Theses/Dissertations from 2018

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Dissertation: Synthesis and Characterization of Glycolipids, Glycoclusters and Glycomacrocycles, Anji Chen

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Dissertation: Development and Evaluation of Post-Production Oxygenation Techniques for the Augmentation of Biochar, Matthew David Huff

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Thesis: Characterizing the Activity of Antimicrobial Peptides Against the Pathogenic Bacterium Clostridium Difficile in an Anaerobic Environment, Adenrele Mojeed Oludiran

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Dissertation: Computational Investigation of Energetic Materials: Influence of Intramolecular and Intermolecular Interactions on Sensitivity, Ashley Lauren Shoaf

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Dissertation: Study of ABC Membrane Transporters in Single Live Cells, Preeyaporn Songkiatisak

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Thesis: The Effect of Soxhlet Extraction and Synthesis Temperature on Properties of Polyaniline, Samuel Watson Stahl

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Dissertation: Structure of the Picornavirus Replication Platform: A Potential Drug Target for Inhibiting Virus Replication, Meghan Suzanne Warden

Theses/Dissertations from 2017

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Dissertation: Observations of Greenhouse Gas Isotopologues with ACE-FTS and WACCM, Eric Michael Buzan

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Dissertation: Alicyclic and Aromatic Carboxylic Acids in Soil Organic Matter: An Investigation of Potential Origin and Association with Plutonium Using Advanced Analytical Techniques, Nicole DiDonato

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Thesis: Characterization of 3-Ester and 3-Carbamate Derivatives of N-Acetyl-D-Glucosamine and Their Use in Controlled Drug Delivery, Consuelo Garcia

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Dissertation: Synthesis, Characterization and Application of Sugar-Based Low Molecular Weight Gelators, Ifeanyi Simeon Okafor

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Dissertation: Lignin Contribution to the Global Carbon Pool: Investigating the Abiotic Modification of Lignin by Reactive Oxygen Species, Derek Charles Waggoner

Theses/Dissertations from 2016

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Thesis: Synthesis and Mechanistic Investigations of Transition Metal Complexes and Ligands for Chemotherapeutic Applications, Jimmie Lee Bullock Jr.

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Dissertation: Design of Drug Nano-Carriers for Study of Multidrug Resistance in Single Live Cells, Pavan Kumar Cherukuri

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Dissertation: Synthesis, Morphological Control, Dispersion Stabilization and In Situ Self-Assembly of Noble Metal Nanostructures Using Multidentate Resorcinarene Surfactants, Sangbum Han

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Thesis: Discoloration of a Green Pigment in Tintoretto’s Allegorical Figure of Spring and Analysis of the Chemical Properties and Stability of Copper Resinate, Sarah Wells Conner Horn

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Dissertation: Low-Temperature Artificial Maturation Studies of Type II and Type III Kerogens: Implications for Biogenic Gas Production, Albert Willy Nguena Kamga

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Dissertation: Bioenergetics: Experimental Demonstration of Excess Protons and Related Features, Haitham A. Saeed

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Dissertation: Possible Sources and Impacts of Biochar Water Extractable Organic Compounds on Aquatic Microorganisms, Cameron Russell Smith

Theses/Dissertations from 2015

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Thesis: Synthesis, Characterisation, Electrochemical, and Spectroscopic Studies of Cobaloximes: Unique Clues of Cobalt(I) Species in Various Solvents, Michael John Celestine

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Dissertation: Computational Investigation of Pernicious Compounds: Arsenic and High Energy Density Materials and Their relevant Mechanisms, Lenora Kathleen Harper

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Dissertation: Artificial Maturation Studies of Polymethylenic Plant Biopolymers: Investigating the Chemical Alterations from Plant Material to Coal, Blaine Elizabeth Hartman

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Dissertation: Investigation of the Potential for Algaenan to Produce Hydrocarbon Based Fuels From Algae by Hydrous Pyrolysis, Wassim Adel Obeid

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Dissertation: Exploring the Effect of Climate Change on Biological Systems, Nardos Sori

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Dissertation: Study of Photochemical Formation of Hydroxyl Radical in Natural Waters, Luni Sun

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Dissertation: Source-Specific Molecular Signatures for Light-Absorbing Organic Aerosols, Amanda Susan Willoughby

Theses/Dissertations from 2014

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Dissertation: Spectroscopic Characterization of Dissolved Organic Matter: Insights Into the Linkage Between Sources and Chemical Composition, Xiaoyan Cao

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Dissertation: Molecular Characterization and Photochemical Transformation of Dissolved Organic Matter From Land to Ocean, Hongmei Chen

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Dissertation: Density Functional Theory Modeling of It-Stacking and Electrophilic Donor-Acceptor Interactions with Application to Therapeutic Targeting of Zinc-Finger Proteins, Patricia Beall Lutz

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Dissertation: Synthesis and Characterization of Sugar Based Low Molecular Weight Gelators and the Preparation of Chiral Sulfinamides, Hari Prasad Reddy Mangunuru

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Dissertation: Advances in Understanding the Molecular Composition of Dissolved Organic Matter and Its Reactivity in the Environment, Rajaa Mesfioui

Theses/Dissertations from 2013

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Dissertation: Novel Algorithms and Instrumentation for Vibrational Spectroscopic Methods of Analysis, Mohamed F. Abdelkader

Theses/Dissertations from 2012

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Dissertation: Spectroscopic Characterization of Dissolved Organic Matter: Insights into Composition, Photochemical Transformation and Carbon Cycling, John Robert Helms

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Thesis: Multidentate Resorcinarene Surfactants for the Phase Transfer of Metal Nanoparticles and Nanodiamonds: Applications in Catalysis and Diamond Film Growth, Vara Prasad Sheela

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Thesis: Identification of Persistent Long Range Interactions in GA95 and GB95 Through Thermal Unfolding Simulations, Milen Redai Tesfamariam

Theses/Dissertations from 2011

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Dissertation: Computational Investigation of the Bioactive Selenium Compounds Ebselen and Selenious Acid, Sonia Antony

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Dissertation: Bioinformatics, Thermodynamics and Kinetics Analysis of an All Alpha Helical Protein with a Gree-Key Topology, Hai Li

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Thesis: Insights into Chemical Structure Changes of Kerogen from Bituminous Coal in Response to Dike Intrusions Investigated by Advanced Solid-State 13C NMR, Yuan Li

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Dissertation: The Nature, Origin and Preservation of Amide Organic Nitrogen in Organic Matter, Georgina Anne McKee

Theses/Dissertations from 2010

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Thesis: Comparison of Ice Core Dissolved Organic Matter from a Greenland Ice Core by Nanospray Fourier Transform Ion Cyclotron Resonance Mass Spectrometry, Joshua Jeremiah Shiloh Marsh

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Thesis: Molecular Characterization of The Soluble Fraction of Atmospheric Particulate Matter Obtained by Chemical Oxidation With Nitric Acid, Amanda Susan Priest

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Dissertation: Conformational Change and Topological Stability of Proteins, Jeffrey Andrew Tibbitt

Theses/Dissertations from 2009

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Dissertation: The Use of Fourier Transform (FT) Surface-Enhanced Raman Scattering for Biochemical Analysis, Robert Butler Jeffers

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Thesis: Solvent Dependent Morphologies in Thiol-ene Photopolymerization: A Facile Route to Synthesis of Resorcinarene Nanocapsules, Zaharoula Marie Kalaitzis

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Dissertation: Export of Terrestrial Dissolved Organic Matter Along a River to Ocean Transect of the Lower Chesapeake Bay Investigated by Advanced Analytical Techniques, Rachel Leigh Sleighter

Theses/Dissertations from 2008

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Thesis: The Regulation of Endothelial and Neuronal Nitric Oxide Synthase Expression in the Preglomerular Vessels by the Increase in Intracellular Calcium Concentration, Stephanie Thomas Montgomery

Theses/Dissertations from 2006

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Thesis: Development of Single Nanoparticle Optical Assays for Imaging Single Living Cells, William John Brownlow

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Thesis: Spectral Shape as an Indicator of Molecular Weight in Chromophoric Dissolved Organic Matter, John Robert Helms

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Thesis: Biochemical Profiling of Gout Patients, Tamera Fayre Schlitt

Theses/Dissertations from 2005

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Thesis: Development and Application of a GG-IRMS Reductive Pyrolysis Reactor Interface for the δ34S Determination of Sulfur in Individual Organic Compounds, N. Deborah Hewlett

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Thesis: Natural and Synthetic Viniferins Associated with the Grapevine Disease Young Vine Decline, David Michael McGinnis

Theses/Dissertations from 2004

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Thesis: Bacterial Degradation of Disinfection By-Products in Drinking Water, Laura Inga Fauntleroy

Theses/Dissertations from 2003

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Thesis: Synthesis and Biological Evaluation of Novel Capacitative Calcium Entry Blockers, Thadigiri Celina Mala

Theses/Dissertations from 2002

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Thesis: Styrene Monomer Solubility in Artificial and Natural Seawaters of the Lower Chesapeake Bay, Eric Joseph Miller

Theses/Dissertations from 2001

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Thesis: Positive Regulation of PKA on Human Gonadotropin-Releasing Hormone (hGnRH) Gene Expression in Human Placental JEG-3 Cells, Zhaoyang Wen

Theses/Dissertations from 2000

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Thesis: Copper Complexation and Speciation in the Western South and Equatorial Atlantic Ocean, John A. Consolvo

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Thesis: Cytotoxic T Cell Response to Influenza Vaccination in Older Adults, Caroline R. Letter

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Thesis: Induction of Apoptosis in Human Prostate Cancer Cells by Resveratrol, Gary Zulfikar Morris

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Thesis: Fourier Transform Raman Spectroscopy for Process Control in the Petroleum Industry, Kent Lawson Wise

Theses/Dissertations from 1999

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Thesis: Zinc Speculation and Ligand Fluxes in Chesapeake Bay and Elizabeth River Pore Waters, Duncan Glover Byers

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Thesis: Generation of Human chorionic gonadotropin Beta Subunit Specific Monoclonal Antibody Using a Synthetic Peptide, Zhe Huang

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Thesis: A Study on the Effects of the N-Terminal Amino Acid Sequence on the Activation of Human T-Cell Leukemia Virus Type 1 Protease, Hidayah Muhammad Kendall

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Thesis: Humic Substances as Interferences in the Analysis of Nitrite in Water, Stephanie Ann Tebault

Theses/Dissertations from 1998

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Thesis: Explosive Vapor Generation and Sampling in Conjunction with Ion Mobility Spectrometry, Saeed H. Almeer

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Thesis: Determination of the N-Terminal Amino Acid Residues on Polypeptides in Secondary Wastewaters, Edward L. Creecy

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Thesis: Developmental and Hormonal Regulation of the Expression of Cytosolic Phospholipase A2 Protein Levels in Baboon Placenta, Kathleen Elizabeth Dunstan

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Thesis: Development of Fluorescent Techniques in the Kinetic Characterization of Reverse Transcriptase, Kevin Kevin Howerton

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Thesis: Chemical Modification of CVD Diamond Electrodes, Robert Matthew Johnson

Theses/Dissertations from 1997

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Thesis: Evaluation of Solid Phase Extraction Followed by Supercritical Fluid Elution of Semi-Volatile Organic Compounds in Toxicity Characteristic Leachates, William Edward Corl III

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Thesis: The Effect of Growth Hormone Release on Plasma and Erythrocyte Selenium and Zinc Levels in Children, Maria Estela Legal de Reid

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Thesis: Fabrication and Evaluation of Boron-Doped CVD Diamond Microelectrodes, Song Pang

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Thesis: Development of Solid Phase Microextraction Methods for Contraband Drugs, Vangielynn Cruz Tersol

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Thesis: Speciation of Selenium in Serum, Alice Tsapayi-Musapatike