A selection of faculty publications from the Department of Biomedical and Translational Sciences, Eastern Virginia Medical School, Macon & Joan Brock Virginia Health Sciences at Old Dominion University.

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Submissions from 2025

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Neuroinflammatory Signaling and Immune Cell Infiltration Differ in Brains of Rats Exposed to Space Radiation and Social Isolation, Austin M. Adkins, Zachary N. M. Luyo, Alea F. Boden, Riley S. Heerbrandt, Richard A. Britten, Laurie L. Wellman, and Larry D. Sanford

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Educational Case: Disseminated Intravascular Coagulation in a Patient with Cancer, Kripa Ahuja and Richard M. Conran

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Antibiotic Resistance: The Growing Threats and Potential Solutions, Olisaemeka Zikora Akunne, Blessing Nkechi Emmanuel, Umar Faruk Saidu, Ayobami Sunday Akinnawo, Nasiru Ademola Adeyemi, Livia Chinaza Egoh, Malami Aishatu Muhammad, Olusegun Ayo Ade-adekunle, Deborah Ahuoyiza Peter, and Anne Amina Freitas

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Loneliness Associates with Endothelial Dysfunction in a Community-Based Cohort: A Pilot Study and Translational Approach, Yvonne Baumer, Brian A. Tirado, Lola R. Ortiz-Whittingham, Andrew S. Baez, Cristhian A. Gutierrez-Huerta, Laurel G. Mendelsohn, Abhinav Saurabh, Joshua A. Jacobs, Marcus R. Andrews, Valerie M. Mitchell, Billy S. Collins, Antwan Jones, Danielle M. Schwartz, Anca D. Dobrian, Michael V. Stanton, and Tiffany M. Powell-Wiley

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Codon Composition in Human Oocyters Reveals Age-Associated Defects in mRNA Decay, Pavla Brachova, Lane K. Christenson, and Nehemiah S. Alvarez

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Drone-Based Medication Delivery for Rural, Flood-Prone Coastal Cities, Yin-Hsuen Chen, Amro M. El-Adle, Kevin J. O'Brien, Taylor Wentworth, and Heather G. Richter

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Using Virtual Reality to Assist Students at Academic Risk in Human Anatomy, Michael Foley, Lauren T. Lilley, Lindsay Meyers, Robert Armstrong, Lisa Fore-Arcand, Kelly McCoy, Chad Eitel, Tod R. Clapp, and Natascha Heise

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Clinical Pharmacology and Medication Safety: A Remote Learning Elective Designed for Senior Medical Students, Elizabeth B. Graham, William T. Wightkin, Curt R. Bay, and Uzoma S. Ikonne

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HIV Protein TAT Dysregulates Multiple Pathways in Human iPSCs- Derived Microglia, Liam Liyang Guo, Robert Jiang, Yan Cheng, Brooke Russell, Yan Y. Sanders, and Ming-Lei Guo

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Ancestry-Dependent Immunologic and Prognostic Effects Characterize the Prostate Cancer Urinary Proteome, Annie Ha, Jaron Arbet, Zhuyu Qiu, Amanda Khoo, Brian P. Main, Meinusha Govindarajan, Matthew Waas, Stanley K. Liu, O. John Semmes, Julius O. Nyalwidhe, Paul C. Boutros, and Thomas Kislinger

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Protein Marker-Dependent Drug Discovery Targeting Breast Cancer Stem Cells, Ashley V. Huang, Yali Kong, Kan Wang, Milton L. Brown, and David Mu

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Swinging Lever Mechanism of Myosin Directly Shown by Time-Resolved Cryo-EM, David P. Klebl, Sean N. McMillan, Cristina Risi, Eva Forgacs, Betty Virok, Jennifer L. Atherton, Sarah A. Harris, Michele Stofella, Donald A. Winkelmann, Frank Sobott, Vitold E. Galkin, Peter J. Knight, Stephen P. Muench, Charlotte A. Scarfi, and Howard D. White

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Interaction of Cardiac Leiomodin with the Native Cardiac Thin Filament, Madison Little, Cristina M. Risi, Tania M. Larrinaga, Mason D. Summers, Tyler Nguyen, Garry E. Smith Jr., Jennifer Atherton, Carol C. Gregorio, Alla S. Kostyukova, and Vitold E. Galkin

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Neurotensin Drives Theca Cell Migration During Ovulation in Primates, Jessica S. Miller, Megan A. G. Sage, Thomas E. Curry Jr., and Diane M. Duffy

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Cannabinoid-2 Receptor Activation Attenuates Sulfur Mustard Analog 2-Chloroethyl-Ethyl-Sulfide-Induced Acute Lung Injury in Mice, Gregory Nicholson, Nicholas Richards, Janette Lockett, My Boi Ly, Raj V. Nair, Woong-Ki Kim, K. Yaragudri Vinod, and Nagaraja Nagre

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Neurotensin Regulates Primate Ovulation Via Multiple Neurotensin Receptors, Andrew C. Pearson, Jessica S. Miller, Hannah J. Jensen, Ketan Shrestha, Thomas E. Curry Jr., and Diane M. Duffy

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Cellular and Molecular Mechanisms of Lung Regeneration, Repair, and Fibrosis, Volume II, Yong Qiu, Xiao Xiao Tang, Shigeyuki Shichino, Prem Prakash Kushwaha, Yan Y. Sanders, Remo Castro Russo, and Chunheng Mo

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Educational Case: Bullous pemphigoid, Ryan C. Saal, Alice A. Roberts, and Richard M. Conran

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Benchmarking Batch-Effect Correction Methods Towards the Construction of a Triple-Negative Breast Cancer Cell Atlas, Peter Scheible, Amy H. Tang, Jing He, and Jiangwen Sun

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EEG Spectral Analysis of Nighttime Sleep and Daytime MSLTs and Neurocognitive Evaluations in Subjects with co-morbid insomnia and OSA, Yuan Shi, Yuru Nie, Fengyi Hao, Xujun Feng, Ye Zhang, Larry D. Sanford, Rong Ren, and Xiangdong Tang

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The Central Role for Troponin C Amino-Terminal ⍺-Helix in Vertebrate Thin Filiment Ca²⁺-Activation, Yun Shi, Lauren A. Blackwell, Ryan K. Schroy, B. Max Cleland, Cristina M. Risi, Michelle S. Parvatiyar, Jose R. Pinto, Vitold E. Galkin, and P. Bryant Chase

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Deletion of CHOP in Beta Cell Protects Mice From Cardiovascular Complications in Type 2 Diabetes: Evidence from a Pre-Clinical Mouse Model, Balaji Srinivas, Kiran Alluri, Nour-Eddine Rhaleb, and Khalid Matrougui

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Epigenetic Regulation in Fibrosis, Qingping Wei, Xiaoru Hu, and Yan Sanders

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Implementing a Chatbot to Promote Hereditary Breast & Ovarian Cancer Genetic Screening in Women's Health: Identifying Barriers and Facilitators to Screening Adoption, Easton N. Wollney, Shireen Madani Sims, Luisel J. Ricks-Santi, Elizabeth Eddy, Daniel Wiesman, and Carla L. Fisher

Submissions from 2024

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Radiation Induced Skin Fibrosis (RISF): Opportunity for Angiotensin II-Dependent Intervention, Patricia F. Boothe, Vidya P. Kumar, Yali Kong, Kan Wang, Howard Levinson, David Mu, and Milton L. Brown

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Synthesis and Structure-Activity Relationship of Boronic Acid Bioisosteres of Combretastatin A-4 as Anticancer Agents, Yali Kong, Michael C. Edler, Ernest Hamel, Asa R. Britton-Jenkins, Omar Gillan, Susan L. Mooberry, David Mu, and Milton L. Brown

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Exploring Angiotensin II and Oxidative Stress in Radiation-Induced Cataract Formation: Potential for Therapeutic Intervention, Vidya P. Kumar, Yali Kong, Riana Dolland, Sandra R. Brown, Kan Wang, Damian Dolland, David Mu, and Milton L. Brown